[HTML][HTML] Effects of chemotherapeutic agents on male germ cells and possible ameliorating impact of antioxidants

S Ghafouri-Fard, H Shoorei, A Abak, M Seify… - Biomedicine & …, 2021 - Elsevier
Abstract Treatment of cancer in young adults is associated with several side effects,
particularly in the reproductive system. Detrimental effects of chemotherapy on the germ …

[HTML][HTML] Recent findings on thymoquinone and its applications as a nanocarrier for the treatment of cancer and rheumatoid arthritis

RR Pal, V Rajpal, P Singh, SA Saraf - Pharmaceutics, 2021 - mdpi.com
Cancer causes a considerable amount of mortality in the world, while arthritis is an
immunological dysregulation with multifactorial pathogenesis including genetic and …

Effects of probiotic supplementation on very low dose AFB1-induced neurotoxicity in adult male rats

GA Sahin, D Karabulut, G Unal, M Sayan, H Sahin - Life Sciences, 2022 - Elsevier
Abstract Aims Aflatoxin B1 (AFB1) is the most toxic and common form of AF found in food
and feed. Although AFB1 exposure has toxic effects on many organs, studies on the brain …

[HTML][HTML] Antioxidant and cytoprotective effects of Nigellasativa L. seeds on the testis of monosodium glutamate challenged rats

M Abd-Elkareem, MAM Abd El-Rahman, NSA Khalil… - Scientific reports, 2021 - nature.com
Monosodium glutamate (MSG) is one of the most widely spread food additives that might
cause male infertility. However, Nigella sativa L. seeds (NSS) could provide a solution. This …

Therapeutic effects of thymoquinone in doxorubicin‐induced hepatotoxicity via oxidative stress, inflammation and apoptosis

AT Akin, E Öztürk, E Kaymak… - Anatomia, histologia …, 2021 - Wiley Online Library
Cancer is a lethal disease that is characterized by uncontrolled cell division and
proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic …

Thymoquinone has a neuroprotective effect against inflammation, oxidative stress, and endoplasmic reticulum stress in the brain cortex, medulla, and hippocampus …

E Kaymak, AT Akin, E Öztürk… - … of Biochemical and …, 2021 - Wiley Online Library
Although doxorubicin (DOX) is used in many cancer treatments, it causes neurotoxicity. In
this study, the effect of thymoquinone (THQ), a powerful antioxidant, on DOX‐induced …

[HTML][HTML] The protective effect of Nigella sativa seeds against monosodium glutamate-induced hepatic dysfunction in rats

M Abd-Elkareem, M Soliman, MAM Abd El-Rahman… - Toxicology Reports, 2022 - Elsevier
Monosodium glutamate (MSG) is one of the most commonly used feed additives which
poses a threat to public health. Nigella sativa is a promising natural approach in this issue …

Isorhamnetin: a flavonoid, attenuated doxorubicin-induced testicular injury via regulation of steroidogenic enzymes and apoptotic signaling gene expression in male …

S Mustafa, MU Ijaz, Q ul Ain, T Afsar… - Toxicology …, 2022 - academic.oup.com
Background Male reproductive damage is one of the most adverse side effects of
doxorubicin (DOX). Isorhamnetin is a natural flavonoid, which displays remarkable …

[HTML][HTML] Prospective affirmative therapeutics of cannabidiol oil mitigates doxorubicin-induced abnormalities in kidney function, inflammation, and renal tissue changes

NA Soliman, SIE Dahmy, AA Shalaby… - Naunyn-Schmiedeberg's …, 2024 - Springer
Nephropathy is the decline in kidney function. A promising treatment for numerous types of
illness is using natural materials as natural chemical compounds. The inquiry was …

Chlorogenic acid co‐administration abates tamoxifen‐mediated reproductive toxicities in male rats: an experimental approach

SE Owumi, RA Anaikor, UO Arunsi… - Journal of Food …, 2021 - Wiley Online Library
Reports over the years have demonstrated toxic side effect–including reproductive toxicity‐
of tamoxifen (TAM), a drug of choice in the management of primary breast cancer …