Pathophysiology of blood–brain barrier permeability throughout the different stages of ischemic stroke and its implication on hemorrhagic transformation and recovery
The blood–brain barrier (BBB) is a dynamic interface responsible for maintaining the central
nervous system homeostasis. Its unique characteristics allow protecting the brain from …
nervous system homeostasis. Its unique characteristics allow protecting the brain from …
Blood-brain barrier dysfunction and recovery after ischemic stroke
The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …
Response of the cerebral vasculature following traumatic brain injury
The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
Blood− brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury
R Prakash, ST Carmichael - Current opinion in neurology, 2015 - journals.lww.com
Our understanding of BBB breakdown acutely after the cerebrovascular injury has come a
long way; however, we lack a clear understanding of the course of BBB disruption and BBB …
long way; however, we lack a clear understanding of the course of BBB disruption and BBB …
Neural stem cell therapy for subacute and chronic ischemic stroke
AC Boese, QSE Le, D Pham, MH Hamblin… - Stem cell research & …, 2018 - Springer
Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …
Vascular remodeling after ischemic stroke: mechanisms and therapeutic potentials
The brain vasculature has been increasingly recognized as a key player that directs brain
development, regulates homeostasis, and contributes to pathological processes. Following …
development, regulates homeostasis, and contributes to pathological processes. Following …
The role of the blood–brain barrier during neurological disease and infection
A Patabendige, D Janigro - Biochemical Society Transactions, 2023 - portlandpress.com
A healthy brain is protected by the blood–brain barrier (BBB), which is formed by the
endothelial cells that line brain capillaries. The BBB plays an extremely important role in …
endothelial cells that line brain capillaries. The BBB plays an extremely important role in …
Endothelium-targeted deletion of microRNA-15a/16-1 promotes poststroke angiogenesis and improves long-term neurological recovery
Rationale: Angiogenesis promotes neurological recovery after stroke and is associated with
longer survival of stroke patients. Cerebral angiogenesis is tightly controlled by certain …
longer survival of stroke patients. Cerebral angiogenesis is tightly controlled by certain …
Time-dependent dual effect of microglia in ischemic stroke
P Fan, S Wang, S Chu, N Chen - Neurochemistry international, 2023 - Elsevier
Stroke, the third leading cause of death and disability worldwide, is classified into ischemic
or hemorrhagic, in which approximately 85% of strokes are ischemic. Ischemic stroke occurs …
or hemorrhagic, in which approximately 85% of strokes are ischemic. Ischemic stroke occurs …
Neural stem cells for early ischemic stroke
MH Hamblin, JP Lee - International journal of molecular sciences, 2021 - mdpi.com
Clinical treatments for ischemic stroke are limited. Neural stem cell (NSC) transplantation
can be a promising therapy. Clinically, ischemia and subsequent reperfusion lead to …
can be a promising therapy. Clinically, ischemia and subsequent reperfusion lead to …