Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies
Genome-wide association studies (GWASs) have identified many SNPs associated with
various common diseases. Understanding the biological functions of these identified SNP …
various common diseases. Understanding the biological functions of these identified SNP …
Robust and rigorous identification of tissue-specific genes by statistically extending tau score
Objectives In this study, we aimed to identify tissue-specific genes for various human
tissues/organs more robustly and rigorously by extending the tau score algorithm …
tissues/organs more robustly and rigorously by extending the tau score algorithm …
Elucidating gene expression patterns across multiple biological contexts through a large-scale investigation of transcriptomic datasets
RQ Figueiredo, SD Del Ser, T Raschka… - BMC …, 2022 - Springer
Distinct gene expression patterns within cells are foundational for the diversity of functions
and unique characteristics observed in specific contexts, such as human tissues and cell …
and unique characteristics observed in specific contexts, such as human tissues and cell …
Species and population specific gene expression in blood transcriptomes of marine turtles
Background Transcriptomic data has demonstrated utility to advance the study of
physiological diversity and organisms' responses to environmental stressors. However, a …
physiological diversity and organisms' responses to environmental stressors. However, a …
Backup transcription factor binding sites protect human genes from mutations in the promoter
JC Brown - Plos one, 2023 - journals.plos.org
This study was designed to test the idea that the regulatory regions of human genes have
evolved to be resistant to the effects of mutations in their primary function, the control of gene …
evolved to be resistant to the effects of mutations in their primary function, the control of gene …
[PDF][PDF] 48104, USA 4. Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA#: To whom correspondence should be addressed: xzhousph …
L Shang, JA Smith, X Zhou - scholar.archive.org
Genome-wide association studies (GWASs) have identified many SNPs associated with
various common diseases. Understanding the biological functions of these identified SNP …
various common diseases. Understanding the biological functions of these identified SNP …