This article provides a comprehensive review of dehydration assessment and presents a
unique evaluation of the dehydration and performance literature. The importance of …

Introduction This systematic review examines the relationship between blood loss and
clinical signs and explores its use to trigger clinical interventions in the management of …

Abstract Editor's Perspective What We Already Know about This Topic Arterial pressure is a
complex signal that is characterized by three primary components—systolic, diastolic, and …

Background: Clinicians routinely refer to hypotension as a systolic blood pressure (SBP)≤
90 mm Hg. However, few data exist to support the rigid adherence to this arbitrary cutoff. We …

Background: Early reversion of sepsis-induced tissue hypoperfusion is essential for survival
in septic shock. However, consensus regarding the best initial resuscitation strategy is …

Shock is deadly and unpredictable if it is not recognized and treated in early stages of
hemorrhage. Unfortunately, measurements of standard vital signs that are displayed on …

Pulse transit time (PTT) measured as the time delay between invasive proximal and distal
blood pressure (BP) or flow waveforms (invasive PTT [I‐PTT]) tightly correlates with BP. PTT …

Background: Hemorrhagic shock is a leading cause of death in both civilian and battlefield
trauma. Currently available medical monitors provide measures of standard vital signs that …

Lower body negative pressure (LBNP), a model of hemorrhage (Hem), shifts blood to the
legs and elicits central hypovolemia. This study compared responses to LBNP and actual …

Trauma patients with “compensated” internal hemorrhage may not be identified with
standard medical monitors until signs of shock appear, at which point it may be difficult or too …