Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments

M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

Features of third generation photosensitizers used in anticancer photodynamic therapy

IS Mfouo-Tynga, LD Dias, NM Inada… - … and photodynamic therapy, 2021 - Elsevier
Cancer remains a main public health issue and the second cause of mortality worldwide.
Photodynamic therapy is a clinically approved therapeutic option. Effective photodynamic …

Carbohydrate–macrocycle conjugates for biomedical applications

F Yin, JJ Li, B Shi, K Zhang, XL Li, KR Wang… - Materials Chemistry …, 2023 - pubs.rsc.org
Carbohydrates are of great importance in a variety of biological processes, including but not
limited to, energy production, energy storage, protein recognition, immune response, and …

Porphyrin macrocycles: General properties and theranostic potential

R Boscencu, N Radulea, G Manda, IF Machado… - Molecules, 2023 - mdpi.com
Despite specialists' efforts to find the best solutions for cancer diagnosis and therapy, this
pathology remains the biggest health threat in the world. Global statistics concerning deaths …

Sonogashira cross-coupling as a key step in the synthesis of new glycoporphyrins

B Godlewski, D Baran, M de Robichon… - Organic Chemistry …, 2022 - pubs.rsc.org
Glycoporphyrins are an important subclass of the porphyrin family of compounds. They have
been intensively studied because of their biological importance, ie they exhibit increased …

Sequence‐Defined Heteromultivalent Precision Glycomacromolecules Bearing Sulfonated/Sulfated Nonglycosidic Moieties Preferentially Bind Galectin‐3 and Delay …

T Freichel, V Heine, D Laaf… - Macromolecular …, 2020 - Wiley Online Library
Within this work, a new class of sequence‐defined heteromultivalent glycomacromolecules
bearing lactose residues and nonglycosidic motifs for probing glycoconjugate recognition in …

Design, synthesis and biological evaluation of the positional isomers of the galactose conjugates able to target hepatocellular carcinoma cells via ASGPR-mediated …

W Ye, Q Tang, T Zhou, C Zhou, C Fan, X Wang… - European Journal of …, 2024 - Elsevier
Galactose as a recognizing motif for asialoglycoprotein receptor (ASGPR) is a widely
accepted vector to deliver cytotoxic agents in the therapy of hepatocellular carcinoma …

“Click” for precise photodynamic therapy

LKB Tam, DKP Ng - Materials Chemistry Frontiers, 2023 - pubs.rsc.org
Bioorthogonal chemistry has been a powerful tool in chemical biology. It can facilitate the
study of biomolecules in their native environments and enables targeted delivery and …

A glutathione-responsive photosensitizer with fluorescence resonance energy transfer characteristics for imaging-guided targeting photodynamic therapy

JJ Cao, MS Zhang, XQ Li, DC Yang, G Xu… - European Journal of …, 2020 - Elsevier
Here, we have synthesized and characterized a novel activatable photosensitizer (PS) 8a in
which two well-designed boron dipyrromethene (BODIPY) derivatives are utilized as the …

Synthesis of Water-Soluble Thioglycosylated trans-A2B2 Type Porphyrins: Cellular Uptake Studies and Photodynamic Efficiency

V Pandey, MK Raza, P Joshi… - The Journal of Organic …, 2020 - ACS Publications
The synthesis of water-soluble thioglycosylated A2B2 type porphyrins and their zinc (II)
complexes is reported. The water-soluble trans-A2B2 porphyrins were synthesized in two …