Protective and enhancing interactions among dengue viruses 1-4 and Zika virus

LC Katzelnick, S Bos, E Harris - Current Opinion in Virology, 2020 - Elsevier
Dengue viruses 1-4 (DENV 1-4) and Zika virus (ZIKV) are closely related flaviviruses
transmitted by Aedes mosquitoes that co-circulate in Asia, the Americas, Africa, and …

Landscape of monoclonal antibodies targeting zika and dengue: therapeutic solutions and critical insights for vaccine development

V Dussupt, K Modjarrad, SJ Krebs - Frontiers in immunology, 2021 - frontiersin.org
The unprecedented 2015–2016 Zika outbreak in the Americas sparked global concern and
drove the rapid deployment of vaccine and therapeutic countermeasures against this re …

Dengue and Zika virus infections in children elicit cross-reactive protective and enhancing antibodies that persist long term

LC Katzelnick, JV Zambrana, D Elizondo… - Science translational …, 2021 - science.org
Dengue virus serotypes 1 to 4 (DENV1–4) and Zika virus (ZIKV) are mosquito-borne
flaviviruses that induce both virus-specific and broadly reactive antibodies. A first DENV …

Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine

AZ Wec, D Haslwanter, YN Abdiche… - Proceedings of the …, 2020 - National Acad Sciences
A comprehensive understanding of the development and evolution of human B cell
responses induced by pathogen exposure will facilitate the design of next-generation …

Self-enriching electrospun biosensors for impedimetric sensing of zika virus

IAM Frias, LH Vega Gonzales Gil… - … Applied Materials & …, 2021 - ACS Publications
Zika virus (ZIKV) infection is associated with the Guillain–Barré syndrome, and when non-
vector congenital transmission occurs, fetal brain abnormalities are expected. After ZIKV …

Structure-guided paradigm shifts in flavivirus assembly and maturation mechanisms

CMR Nicholls, M Sevvana, RJ Kuhn - Advances in virus research, 2020 - Elsevier
The flavivirus genus encompasses more than 75 unique viruses, including dengue virus
which accounts for almost 390 million global infections annually. Flavivirus infection can …

Basic amino acid substitution at residue 367 of the envelope protein of Tembusu virus plays a critical role in pathogenesis

M Sun, L Zhang, Y Cao, J Wang, Z Yu, X Sun… - Journal of …, 2020 - Am Soc Microbiol
Tembusu virus (TMUV) is a flavivirus responsible for panzootic outbreaks of severe egg-
drop and fatal encephalitis of domestic waterfowl in China. Although TMUV can be …

Immune profile and responses of a novel dengue DNA vaccine encoding an EDIII-NS1 consensus design based on Indo-African sequences

A Sankaradoss, S Jagtap, J Nazir, SE Moula, A Modak… - Molecular Therapy, 2022 - cell.com
The ongoing COVID-19 pandemic highlights the need to tackle viral variants, expand the
number of antigens, and assess diverse delivery systems for vaccines against emerging …

A cathelicidin antimicrobial peptide from Hydrophis cyanocinctus inhibits Zika virus infection by downregulating expression of a viral entry factor

J Wang, B Jiang, K Wang, J Dai, C Dong… - Journal of Biological …, 2022 - ASBMB
Zika virus (ZIKV) is a re-emerging flavivirus that causes conditions such as microcephaly
and testis damage. The spread of ZIKV has become a major public health concern. Recent …

The key amino acids of E protein involved in early flavivirus infection: Viral entry

T Hu, Z Wu, S Wu, S Chen, A Cheng - Virology journal, 2021 - Springer
Flaviviruses are enveloped viruses that infect multiple hosts. Envelope proteins are the
outermost proteins in the structure of flaviviruses and mediate viral infection. Studies indicate …