Natural products: potential treatments for cisplatin-induced nephrotoxicity

C Fang, D Lou, L Zhou, J Wang, B Yang, Q He… - Acta Pharmacologica …, 2021 - nature.com
Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment
of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer …

Chlorogenic acid: A comprehensive review of the dietary sources, processing effects, bioavailability, beneficial properties, mechanisms of action, and future directions

H Lu, Z Tian, Y Cui, Z Liu, X Ma - Comprehensive reviews in …, 2020 - Wiley Online Library
Chlorogenic acids (CGAs), a group of hydroxycinnamates, are generally abundant in
everyday foods and beverages, most prominently in certain coffee drinks. Among them, the …

Chlorogenic acid prevents diabetic nephropathy by inhibiting oxidative stress and inflammation through modulation of the Nrf2/HO-1 and NF-ĸB pathways

L Bao, J Li, D Zha, L Zhang, P Gao, T Yao… - International …, 2018 - Elsevier
Oxidative and inflammatory damage have been suggested to play important roles in the
pathogenesis of diabetic nephropathy (DN). Chlorogenic acid (CGA) is one of the most …

Protective effect of Chlorogenic acid against methotrexate induced oxidative stress, inflammation and apoptosis in rat liver: An experimental approach

N Ali, S Rashid, S Nafees, SK Hasan, A Shahid… - Chemico-biological …, 2017 - Elsevier
Methotrexate (MTX) is a drug which is used to treat different types of cancers but
hepatotoxicity limits its clinical use. Chlorogenic acid (CGA) is one of the most abundant …

Phenolic compounds from five Ericaceae species leaves and their related bioavailability and health benefits

BE Ștefănescu, K Szabo, A Mocan, G Crişan - Molecules, 2019 - mdpi.com
Some species of the Ericaceae family have been intensively studied because of the
beneficial health impact, known since ancient times, of their chemical components. Since …

Evaluation of antidiabetic activity of dietary phenolic compound chlorogenic acid in streptozotocin induced diabetic rats: Molecular docking, molecular dynamics, in …

AK Singh, HK Rana, V Singh, TC Yadav… - Computers in biology …, 2021 - Elsevier
Background Chlorogenic acid is amongst the well-known polyphenolic compounds being
used in human food and beverages. Its presence has been reported in tea leaves, roasted …

Chlorogenic Acid Alleviates Aβ25-35-Induced Autophagy and Cognitive Impairment via the mTOR/TFEB Signaling Pathway

L Gao, X Li, S Meng, T Ma, L Wan… - Drug design, development …, 2020 - Taylor & Francis
Purpose Chlorogenic acid (CGA), a phenolic acid isolated from fruits and vegetables, has
been established to have neuroprotective properties in relation to Alzheimer's disease (AD) …

Chlorogenic acid induces 4T1 breast cancer tumor's apoptosis via p53, Bax, Bcl‐2, and caspase‐3 signaling pathways in BALB/c mice

Z Changizi, A Moslehi, AH Rohani… - Journal of Biochemical …, 2021 - Wiley Online Library
Despite all the new treatments, metastatic breast cancer (BC) causes many deaths.
Chlorogenic acid (CGA) is a polyphenol compound with various pharmacological traits, such …

A review of the protective effects of chlorogenic acid against different chemicals

R Rashidi, R Rezaee, A Shakeri… - Journal of Food …, 2022 - Wiley Online Library
Chlorogenic acid (CGA) is a naturally occurring non‐flavonoid polyphenol found in green
coffee beans, teas, certain fruits, and vegetables, that exerts antiviral, antitumor …

Ginsenoside Rg5 ameliorates cisplatin-induced nephrotoxicity in mice through inhibition of inflammation, oxidative stress, and apoptosis

W Li, MH Yan, Y Liu, Z Liu, Z Wang, C Chen, J Zhang… - Nutrients, 2016 - mdpi.com
Although cisplatin is an effective anti-cancer agent that is widely used for treating various
types of malignant solid tumors, the nephrotoxicity induced by cisplatin severely limits its …