[HTML][HTML] Update on the impact, diagnosis and management of cardiovascular autonomic neuropathy in diabetes: what is defined, what is new, and what is unmet

V Spallone - Diabetes & metabolism journal, 2019 - synapse.koreamed.org
The burden of diabetic cardiovascular autonomic neuropathy (CAN) is expected to increase
due to the diabetes epidemic and its early and widespread appearance. CAN has a definite …

Autonomic nervous system activity changes in patients with hypertension and overweight: role and therapeutic implications

P Valensi - Cardiovascular diabetology, 2021 - Springer
The incidence and prevalence of hypertension is increasing worldwide, with approximately
1.13 billion of people currently affected by the disease, often in association with other …

GDF15 promotes weight loss by enhancing energy expenditure in muscle

D Wang, LK Townsend, GJ DesOrmeaux, SM Frangos… - Nature, 2023 - nature.com
Caloric restriction that promotes weight loss is an effective strategy for treating non-alcoholic
fatty liver disease and improving insulin sensitivity in people with type 2 diabetes. Despite its …

The pathogenesis of obesity

SM Oussaada, KA Van Galen, MI Cooiman… - Metabolism, 2019 - Elsevier
Body fat mass increases when energy intake exceeds energy expenditure. In the long term,
a positive energy balance will result in obesity. The worldwide prevalence of obesity has …

Gender differences and cardiometabolic risk: the importance of the risk factors

A Meloni, C Cadeddu, L Cugusi… - International journal of …, 2023 - mdpi.com
Metabolic syndrome (Mets) is a clinical condition characterized by a cluster of major risk
factors for cardiovascular disease (CVD) and type 2 diabetes: proatherogenic dyslipidemia …

Autonomic nervous system development and its impact on neuropsychiatric outcome

SB Mulkey, AJ du Plessis - Pediatric Research, 2019 - nature.com
The central autonomic nervous system (ANS) is essential for maintaining cardiovascular and
respiratory homeostasis in the newborn and has a critical role in supporting higher cortical …

Autonomic nervous system in obesity and insulin-resistance—The complex interplay between leptin and central nervous system

B Russo, M Menduni, P Borboni, F Picconi… - International Journal of …, 2021 - mdpi.com
The role of the autonomic nervous system in obesity and insulin-resistant conditions has
been largely explored. However, the exact mechanisms involved in this relation have not …

Cardiac autonomic neuropathy in obesity, the metabolic syndrome and prediabetes: a narrative review

SM Williams, A Eleftheriadou, U Alam, DJ Cuthbertson… - Diabetes Therapy, 2019 - Springer
Cardiac autonomic neuropathy (CAN) is a major complication of type 1 and type 2 diabetes
mellitus (T1DM and T2DM). The increased morbidity, cardiovascular and all-cause mortality …

Improving obesity and blood pressure

M Tanaka - Hypertension Research, 2020 - nature.com
Obesity-associated hypertension is a serious public health concern. Sympathetic nervous
system (SNS) overactivity, especially in the kidneys, is an important mechanism linking …

Hypertension as a metabolic disorder and the novel role of the gut

M Tanaka, H Itoh - Current hypertension reports, 2019 - Springer
Abstract Purpose of Review Hypertension is related to impaired metabolic homeostasis and
can be regarded as a metabolic disorder. This review presents possible mechanisms by …