Sphingolipids, including the two central bioactive lipids ceramide and sphingosine-1-
phosphate (S1P), have opposing roles in regulating cancer cell death and survival …

The endoplasmic reticulum (ER), which occupies a large portion of the cytoplasm, is the
cell's main site for the biosynthesis of lipids and carbohydrate conjugates, and it is essential …

Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …

Blood group antigens represent polymorphic traits inherited among individuals and
populations. At present, there are 34 recognized human blood groups and hundreds of …

The lipid composition of cellular organelles is tailored to suit their specialized tasks. A
fundamental transition in the lipid landscape divides the secretory pathway in early and late …

Sphingolipids are structurally and functionally diverse molecules with significant physiologic
functions and are found associated with cellular membranes and plasma lipoproteins. The …

Glycosphingolipids (GSL s) comprise a heterogeneous group of membrane lipids formed by
a ceramide backbone covalently linked to a glycan moiety. Hundreds of different glycans …

Simple Summary Sphingolipids are membrane-associated lipids that are involved in signal
transduction pathways regulating cell death, growth, and migration. In cancer cells …

SARS-CoV-2 virions are surrounded by a lipid bilayer that contains membrane proteins such
as spike, responsible for target-cell binding and virus fusion. We found that during SARS …

Niemann–Pick type C disease (NPCD) was first described in 1914 and affects approximately
1 in 150 000 live births. It is characterized clinically by diverse symptoms affecting liver …