As a group of disorders, autoimmunity ranks as the third most prevalent cause of morbidity
and mortality in the W estern W orld. However, the etiology of most autoimmune diseases …

A-to-I RNA editing, the deamination of adenosine (A) to inosine (I) that occurs in regions of
RNA with double-stranded character, is catalyzed by a family of Adenosine Deaminases …

Adenoviruses are used extensively as gene transfer agents, both experimentally and
clinically. However, targeting of liver cells by adenoviruses compromises their potential …

Listeria monocytogenes is responsible for severe food-borne infections, but the mechanisms
by which bacteria cross the intestinal barrier are unknown. Listeria monocytogenes …

Cellular senescence limits proliferation of potentially detrimental cells, preventing
tumorigenesis and restricting tissue damage. However, the function of senescence in …

Abstract Human herpesvirus 6 (HHV-6) is the etiologic agent of exanthema subitum, causes
opportunistic infections in immunocompromised patients, and has been implicated in …

Among cells of the immune system, CD11c+ and DEC-205+ splenic dendritic cells primarily
express the cellular receptor (α-dystroglycan [α-DG]) for lymphocytic choriomeningitis virus …

The interaction of a virus with its cellular receptor initiates a chain of dynamic events that will
enable entry of the virus into the cell. In addition to the fact that the virus–receptor interaction …

Evolution of receptor specificity by viruses has several implications for viral pathogenesis,
host range, virus-mediated gene targeting, and viral adaptation after organ transplantation …

Measles virus (MV), a member of the family Paramyxoviridae and an exclusively human
pathogen, is among the most infectious viruses. A progressive fatal neurodegenerative …