Resistance mechanisms to antimicrobial peptides in gram-positive bacteria

L Assoni, B Milani, MR Carvalho… - Frontiers in …, 2020 - frontiersin.org
With the alarming increase of infections caused by pathogenic multidrug-resistant bacteria
over the last decades, antimicrobial peptides (AMPs) have been investigated as a potential …

Pathogenicity and virulence of Clostridium botulinum

AM Rawson, AW Dempster, CM Humphreys… - Virulence, 2023 - Taylor & Francis
Clostridium botulinum, a polyphyletic Gram-positive taxon of bacteria, is classified purely by
their ability to produce botulinum neurotoxin (BoNT). BoNT is the primary virulence factor …

Pan-Genomic Analysis of Clostridium botulinum Group II (Non-Proteolytic C. botulinum) Associated with Foodborne Botulism and Isolated from the Environment

J Brunt, AHM van Vliet, SC Stringer, AT Carter… - Toxins, 2020 - mdpi.com
The neurotoxin formed by Clostridium botulinum Group II is a major cause of foodborne
botulism, a deadly intoxication. This study aims to understand the genetic diversity and …

SpoIVA is an essential morphogenetic protein for the formation of heat- and lysozyme-resistant spores in Clostridium sporogenes NBRC 14293

R Kuwana, B Dupuy, I Martin-Verstraete… - Frontiers in …, 2024 - frontiersin.org
Clostridium sporogenes is an anaerobic spore-forming bacterium genetically related to
Clostridium botulinum but lacks toxin genes. The sporulation mechanism and spore …

CRISPR-Cas9-Based Toolkit for Clostridium botulinum Group II Spore and Sporulation Research

A Mertaoja, MB Nowakowska, G Mascher… - Frontiers in …, 2021 - frontiersin.org
The spores of Clostridium botulinum Group II strains pose a significant threat to the safety of
modern packaged foods due to the risk of their survival in pasteurization and their ability to …

Phage lysin that specifically eliminates Clostridium botulinum Group I cells

Z Zhang, M Lahti, FP Douillard, H Korkeala… - Scientific Reports, 2020 - nature.com
Clostridium botulinum poses a serious threat to food safety and public health by producing
potent neurotoxin during its vegetative growth and causing life-threatening neuroparalysis …

Occurrence of genes encoding spore germination in Clostridium species that cause meat spoilage

SA Burgess, FP Palevich, A Gardner… - Microbial …, 2022 - microbiologyresearch.org
Members of the genus Clostridium are frequently associated with meat spoilage. The ability
for low numbers of spores of certain Clostridium species to germinate in cold-stored vacuum …