Toxoplasmosis: recent advances in understanding the link between infection and host behavior
SK Johnson, PTJ Johnson - Annual Review of Animal …, 2021 - annualreviews.org
Humans, wildlife, and domestic animals are intimately linked through shared infections.
Many parasites and pathogens use multiple host species, either opportunistically or …
Many parasites and pathogens use multiple host species, either opportunistically or …
Individual differences in inflammatory and oxidative mechanisms of stress-related mood disorders
LS Kalinichenko, J Kornhuber, CP Müller - Frontiers in …, 2019 - Elsevier
Emotional stress leads to the development of peripheral disorders and is recognized as a
modifiable risk factor for psychiatric disorders, particularly depression and anxiety. However …
modifiable risk factor for psychiatric disorders, particularly depression and anxiety. However …
Behavioral alterations in long-term Toxoplasma gondii infection of C57BL/6 mice are associated with neuroinflammation and disruption of the blood brain barrier
L Castaño Barrios, AP Da Silva Pinheiro, D Gibaldi… - Plos one, 2021 - journals.plos.org
The Apicomplexa protozoan Toxoplasma gondii is a mandatory intracellular parasite and
the causative agent of toxoplasmosis. This illness is of medical importance due to its high …
the causative agent of toxoplasmosis. This illness is of medical importance due to its high …
Dulaglutide impedes depressive-like behavior persuaded by chronic social defeat stress model in male C57BL/6 mice: Implications on GLP-1R and cAMP/PKA …
AB Darwish, NS El Sayed, AAA Salama, MA Saad - Life Sciences, 2023 - Elsevier
Aim There is a well-founded relation between bullying and depression, which may
eventually lead to suicidal behavior. Repurposing of antidiabetic drugs for the treatment of …
eventually lead to suicidal behavior. Repurposing of antidiabetic drugs for the treatment of …
Gut microbiota mediates anxiety-like behaviors induced by chronic infection of Toxoplasma gondii in mice
X Luo, X Yang, S Tan, Y Zhang, Y Liu, X Tian… - Gut …, 2024 - Taylor & Francis
Background Chronic infection with the neurotropic parasite Toxoplasma gondii (T. gondii)
can cause anxiety and gut microbiota dysbiosis in hosts. However, the potential role of gut …
can cause anxiety and gut microbiota dysbiosis in hosts. However, the potential role of gut …
Latent toxoplasmosis is associated with depression and suicidal behavior
Objective Neuroinflammation is implicated in the pathophysiology of depression.
Toxoplasma gondii (T. gondii) causes chronic brain inflammatory process and may thus …
Toxoplasma gondii (T. gondii) causes chronic brain inflammatory process and may thus …
Relationship between Toxoplasma gondii seropositivity and depression in children and adolescents
ŞY Sapmaz, S Şen, Y Özkan, H Kandemir - Psychiatry Research, 2019 - Elsevier
Identification of the structural causes of depression is important for the treatment process,
and toxoplasmosis may be related to psychiatric disorders. The aim of this study was to …
and toxoplasmosis may be related to psychiatric disorders. The aim of this study was to …
Genetically predisposed and resilient animal models of depression reveal divergent responses to early-life adversity
AJ Whitney, Z Lindeque, R Kruger… - Acta neuropsychiatrica, 2024 - cambridge.org
Objective: Early-life adversity (ELA) is one of the strongest predictors of childhood
depression that may be exacerbated by a genetic predisposition to develop depression. We …
depression that may be exacerbated by a genetic predisposition to develop depression. We …
Arctigenin ameliorates depression-like behaviors in Toxoplasma gondii-infected intermediate hosts via the TLR4/NF-κB and TNFR1/NF-κB signaling pathways
JH Cheng, X Xu, YB Li, XD Zhao, F Aosai… - International …, 2020 - Elsevier
Toxoplasma gondii (T. gondii) is a known neurotropic protozoan that remains in the central
nervous system and induces neuropsychiatric diseases in intermediate hosts. Arctigenin …
nervous system and induces neuropsychiatric diseases in intermediate hosts. Arctigenin …
Sulfadiazine plus pyrimethamine therapy reversed multiple behavioral and neurocognitive changes in long-term chronic toxoplasmosis by reducing brain cyst load …
Toxoplasma gondii infects one-third of the world population. For decades, it has been
considered a silent lifelong infection. However, chronically T. gondii-infected persons may …
considered a silent lifelong infection. However, chronically T. gondii-infected persons may …