Irrespective of the morphological features of end-stage cell death (that may be apoptotic,
necrotic, autophagic, or mitotic), mitochondrial membrane permeabilization (MMP) is …

Psychological stresses are associated with cardiovascular diseases to the extent that
cardiovascular diseases are among the most important group of psychosomatic diseases …

Post-mitotic neurons and heart muscle cells undergo apoptotic cell death in a variety of
acute and chronic degenerative diseases. The intrinsic pathway of apoptosis involves the …

Urocortins, three paralogs of the stress-related peptide corticotropin-releasing factor (CRF)
found in bony fish, amphibians, birds, and mammals, have unique phylogenies …

Apoptosis contributes, with necrosis, to the cardiac cell loss after ischemia/reperfusion injury.
The apoptotic cascade is initiated either by mitochondrial damage and activation of caspase …

Corticotropin-releasing factor (CRF) receptor type 2β (CRFR2β) is expressed in the heart.
Urocortin (Ucn)-I activation of CRFR2β is cardioprotective against ischemic reperfusion (I/R) …

Apoptosis, a genetically programmed form of cell death, contributes to myocyte cell loss in a
variety of cardiac pathologies, including cardiac failure and those related to …

Many of the originally identified cardiovascular 'growth factors' have been demonstrated to
exert a diverse variety of actions within the cardiovascular system, the majority of which are …

This study tested the hypothesis that inhibition of myocardial injury and modulation of
mitochondrial dysfunction by postconditioning (Postcon) after 24 h of reperfusion is …

Ten years ago, the first finding of apoptotic cell death on the 'crime scene'of cardiac
ischemia/reperfusion injury profoundly dismayed the scientific community. This observation …