Examines the association of the therapeutic benefit of allogeneic bone marrow
transplantation with immune-mediated graft-versus-malignancy effect. Information on graft …

This article discusses changes in the way hematopoietic stem cell allotransplants may be
carried out in the future to treat patients with malignant hematological diseases. Specifically …

Background Since allogeneic stem-cell transplantation can induce curative graft-versus-
leukemia reactions in patients with hematologic cancers, we sought to induce analogous …

Administration of donor T cells expressing the herpes simplex–thymidine kinase (HS-tk) with
a hematopoietic stem cell (HSC) transplantation could allow, if graft-versus-host disease …

We evaluated demographic characteristics and graft composition as risk factors for acute
graft-versus-host disease (GVHD) in 160 adult recipients of HLA-identical allogeneic blood …

Cellular inactivation through killer immunoglobulin-like receptors (KIRs) may allow
neoplastic cells to evade host natural killer (NK) cell–mediated immunity. Recently …

The feasibility and toxicity of allogeneic stem cell transplantation after nonmyeloablative
conditioning including thiotepa, fludarabine, and cyclophosphamide have been investigated …

Conventional allogeneic stem cell transplantation is a valuable approach to therapy for
many hematologic malignancies. However, high-dose conditioning regimens designed both …

The newly developed immunomodulator tacrolimus (FK506) is the first of a new class of
agents that have enormous potential to change the way that dermatoses are treated and …

We evaluated the feasibility and efficacy of a reduced-intensity conditioning (RIC) regimen of
fludarabine and melphalan to achieve rapid complete donor chimerism after allogeneic stem …