Neuronal death mechanisms and therapeutic strategy in ischemic stroke

R Mao, N Zong, Y Hu, Y Chen, Y Xu - Neuroscience bulletin, 2022 - Springer
Ischemic stroke caused by intracranial vascular occlusion has become increasingly
prevalent with considerable mortality and disability, which gravely burdens the global …

Microglia-mediated neuroinflammation and neuroplasticity after stroke

Y Wang, RK Leak, G Cao - Frontiers in cellular neuroscience, 2022 - frontiersin.org
Stroke remains a major cause of long-term disability and mortality worldwide. The immune
system plays an important role in determining the condition of the brain following stroke. As …

[HTML][HTML] Microenvironment-responsive nanosystems for ischemic stroke therapy

F Wu, Z Zhang, S Ma, Y He, Y He, L Ma, N Lei… - …, 2024 - pmc.ncbi.nlm.nih.gov
Ischemic stroke, a common neurological disorder caused by impaired blood supply to the
brain, presents a therapeutic challenge. Conventional treatments like thrombolysis and …

The Dual Role of Autophagy in Postischemic Brain Neurodegeneration of Alzheimer's Disease Proteinopathy

R Pluta - International Journal of Molecular Sciences, 2023 - mdpi.com
Autophagy is a self-defense and self-degrading intracellular system involved in the recycling
and elimination of the payload of cytoplasmic redundant components, aggregated or …

Therapeutic effect of α 7 nicotinic receptor activation after ischemic stroke in rats

L Aguado, A Joya, M Garbizu… - Journal of Cerebral …, 2023 - journals.sagepub.com
Nicotinic acetylcholine α7 receptors (α7 nAChRs) have a well-known modulator effect in
neuroinflammation. Yet, the therapeutical effect of α7 nAChRs activation after stroke has …

Apitherapy in Post-Ischemic Brain Neurodegeneration of Alzheimer's Disease Proteinopathy: Focus on Honey and Its Flavonoids and Phenolic Acids

R Pluta, B Miziak, SJ Czuczwar - Molecules, 2023 - mdpi.com
Neurodegeneration of the brain after ischemia is a major cause of severe, long-term
disability, dementia, and mortality, which is a global problem. These phenomena are …

Involvement of ceramide metabolism in cerebral ischemia

A Ouro, C Correa-Paz, E Maqueda… - Frontiers in Molecular …, 2022 - frontiersin.org
Ischemic stroke, caused by the interruption of blood flow to the brain and subsequent
neuronal death, represents one of the main causes of disability in worldwide. Although …

Biological Activities of Morita-Baylis-Hillman Adducts (MBHA)

LAM Paiva Ferreira, LM de Lima… - Mini Reviews in …, 2023 - ingentaconnect.com
Background: The Morita-Baylis-Hillman reaction (MBHR) is considered one of the most
powerful and versatile methodologies used for carbon-carbon bond formation. The reaction …

Neuroprotective effect of Potentilla reptans L. root in the rat brain global ischemia/reperfusion model

S Noorgaldi, HB Sarkala, A Enayati, V Khori… - Archiv der …, 2023 - Wiley Online Library
Stroke is the most common cause of death among neurological diseases. The protective
effects of Potentilla reptans L. include antioxidative, anti‐inflammatory, and antiapoptotic …

Identification of dysregulated mechanisms and potential biomarkers in ischemic stroke onset

B Feng, X Meng, H Zhou, L Chen, C Zou… - … Journal of General …, 2021 - Taylor & Francis
Objective Ischemic stroke (IS) is a major cause of severe disability. This study aimed to
identify potential biomarkers closely related to IS diagnosis and treatment. Methods Profiles …