Despite remarkable improvements in cancer treatment approaches, breast cancer is still the
main cause of cancer-related death in women. Its principal cause is the resistance of the …

Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

Introduction: Cancer cells apply various mechanisms to induce and enhance immune
escape. The complex network of immune-response modulating factors in the tumor …

In the past 10 years, with the increase of investment in clinical nano-gene therapy, there are
many trials that have been discontinued due to poor efficacy and serious side effects …

Breast cancer (BC) is known to be a highly heterogeneous disease that is clinically
subdivided into four primary molecular subtypes, each having distinct morphology and …

The efficacy of conventional anti-tumor immunotherapeutic approaches is markedly affected
by the immunosuppressive microenvironment of tumor. Since adenosine is one of the main …

Natural polysaccharides are frequently used in the design of drug delivery systems due to
their biocompatibility, biodegradability, and low toxicity. Moreover, they are diverse in …

Purpose: Nanoparticle (NP)-mediated targeted delivery of therapeutic genes or siRNAs to
tumors has potential advantages. In this study, hyaluronic acid (HA)-modified chitosan …

In the present work, the activated carbon (AC) adsorbent with multimodal pore size
distribution prepared from Amygdalus scoparia as low-cost and locally available source was …

Current treatments for intestinal diseases including inflammatory bowel diseases, irritable
bowel syndrome, and colonic bacterial infections are typically small molecule oral dosage …