[HTML][HTML] Artificial intelligence and statistical methods for stratification and prediction of progression in amyotrophic lateral sclerosis: A systematic review

E Tavazzi, E Longato, M Vettoretti, H Aidos… - Artificial Intelligence in …, 2023 - Elsevier
Abstract Background: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative
disorder characterised by the progressive loss of motor neurons in the brain and spinal cord …

Biclustering data analysis: a comprehensive survey

EN Castanho, H Aidos, SC Madeira - Briefings in Bioinformatics, 2024 - academic.oup.com
Biclustering, the simultaneous clustering of rows and columns of a data matrix, has proved
its effectiveness in bioinformatics due to its capacity to produce local instead of global …

Temporal stratification of amyotrophic lateral sclerosis patients using disease progression patterns

D M. Amaral, DF Soares, M Gromicho… - Nature …, 2024 - nature.com
Identifying groups of patients with similar disease progression patterns is key to understand
disease heterogeneity, guide clinical decisions and improve patient care. In this paper, we …

Biclustering fMRI time series: a comparative study

EN Castanho, H Aidos, SC Madeira - BMC bioinformatics, 2022 - Springer
Background The effectiveness of biclustering, simultaneous clustering of rows and columns
in a data matrix, was shown in gene expression data analysis. Several researchers …

[HTML][HTML] Learning prognostic models using a mixture of biclustering and triclustering: Predicting the need for non-invasive ventilation in Amyotrophic Lateral Sclerosis

DF Soares, R Henriques, M Gromicho… - Journal of Biomedical …, 2022 - Elsevier
Longitudinal cohort studies to study disease progression generally combine temporal
features produced under periodic assessments (clinical follow-up) with static features …

Triclustering-based classification of longitudinal data for prognostic prediction: targeting relevant clinical endpoints in amyotrophic lateral sclerosis

DF Soares, R Henriques, M Gromicho… - Scientific Reports, 2023 - nature.com
This work proposes a new class of explainable prognostic models for longitudinal data
classification using triclusters. A new temporally constrained triclustering algorithm, termed …

Learning prognostic models using disease progression patterns: Predicting the need for non-invasive ventilation in amyotrophic lateral sclerosis

AS Martins, M Gromicho, S Pinto… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
Amyotrophic Lateral Sclerosis is a devastating neurodegenerative disease causing rapid
degeneration of motor neurons and usually leading to death by respiratory failure. Since …

[PDF][PDF] Predicting the functional rating scale and self-assessment status of ALS patients with sensor data

A Martins, D Amaral, E Castanho, D Soares, R Branco… - 2024 - ceur-ws.org
Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease causing
progressive loss of cognitive and motor functions. Due to limited understanding of its …

Ensemble-imbalance-based classification for amyotrophic lateral sclerosis prognostic prediction: identifying short-survival patients at diagnosis

F Papaiz, MET Dourado Jr… - BMC Medical Informatics …, 2024 - Springer
Abstract Prognosticating Amyotrophic Lateral Sclerosis (ALS) presents a formidable
challenge due to patients exhibiting different onset sites, progression rates, and survival …

[PDF][PDF] Hierarchical Modelling for ALS Prognosis: Predicting the Progression Towards Critical Events.

R Branco, DF Soares, AS Martins, E Auletta… - CLEF (Working …, 2022 - ceur-ws.org
Abstract Amyotrophic Lateral Sclerosis is a neurodegenerative disease that leads to a
patient's progressive loss of cognitive and motor capacities. Its mechanisms are poorly …