The discovery of a catalytic RNA within RNase P and its legacy

LA Kirsebom, F Liu, WH McClain - Journal of Biological Chemistry, 2024 - ASBMB
Sidney Altman's discovery of the processing of one RNA by another RNA that acts like an
enzyme was revolutionary in biology and the basis for his sharing the 1989 Nobel Prize in …

A minimal RNA substrate with dual fluorescent probes enables rapid kinetics and provides insight into bacterial RNase P active site interactions

T Huang, A Chamberlain, J Zhu, ME Harris - RSC Chemical Biology, 2024 - pubs.rsc.org
Bacterial ribonuclease P (RNase P) is a tRNA processing endonuclease that occurs
primarily as a ribonucleoprotein with a catalytic RNA subunit (P RNA). As one of the first …