Many, if not most, embryos begin development with extremely short cell cycles that exhibit
unusually rapid DNA replication and no gap phases. The commitment to the cell cycle in the …

Production of functional eggs requires meiosis to be coordinated with developmental
signals. Oocytes arrest in prophase I to permit oocyte differentiation, and in most animals, a …

The piwi family genes are crucial for stem cell self-renewal, RNA silencing, and translational
regulation in diverse organisms. However, their function in mammals remains unexplored …

The testis is a peculiar tissue in many respects. It shows patterns of rapid gene evolution and
provides a hotspot for the origination of genetic novelties such as de novo genes …

This book will give an overview of insect ovaries, showing the diversities and the common
traits in egg growth processes. The idea to write this book developed while looking at the …

Abstract GLIAL-CELL-LINE-DERIVED neurotrophic factor (GDNF) promotes the survival and
phenotype of central dopaminergic1, 2, noradrenergic3 and motor neurons4–6, as well as …

Because maturing oocytes and early embryos lack appreciable transcription,
posttranscriptional regulatory processes control their development. To better understand this …

We describe 83 recessive autosomal male-sterile mutations, generated by single P element
mutagenesis in Drosophila melanogaster. Each mutation has been localized to a lettered …

INFERTILITY resulting from a severe defect in sperm production affects 2% of men
worldwide1, 2. Of these men with azoospermia, the absence of sperm in semen, one in eight …

A century of genetic studies of the meiotic process in Drosophila melanogaster females has
been greatly augmented by both modern molecular biology and major advances in cytology …