The physiological role of estrogen in the female endometrium is well established. On the
basis of responses to steroid hormones (progesterone, androgen, and estrogen), the …

Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-
coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian …

Alterations in estrogen-mediated cellular signaling play an essential role in the
pathogenesis of endometriosis. In addition to higher estrogen receptor (ER) β levels …

Introduction This study presents a unifying concept of the pathophysiology of endometriosis
and adenomyosis. In particular, a physiological model is proposed that provides a …

The steroid hormone progesterone (P4) plays a key role in the reproductive events
associated with pregnancy establishment and maintenance. High concentrations of …

BACKGROUND Endometriosis is usually diagnosed by an invasive procedure such as a
laparoscopy. Great interest therefore lies in the potential to identify biomarkers which may be …

Endometriosis is an estrogen-dependent gynecological disorder, defined as the growth of
endometrial stromal cells and glands at extrauterine sites. Endometriotic lesions are more …

BACKGROUND Patients with endometriosis often experience infertility and have poor IVF
outcomes, with low fertilization and pregnancy rates. Although many theories have tried to …

In spite of the widespread abuse of androgenic steroids by athletes and recreational body-
builders, the effects of these agents on athletic performance and physical function remain …

Conservative surgical treatment for symptomatic endometriosis is frequently associated with
only partial relief of pelvic pain or its recurrence. Therefore, medical therapy constitutes an …