From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery
KCF Bordon, CT Cologna, EC Fornari-Baldo… - Frontiers in …, 2020 - frontiersin.org
Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
Research status and development potential of composite hemostatic materials
Bleeding is a serious incident that can occur in people's daily lives or clinics. Bleeding can
be caused by accidental trauma, surgery, congenital diseases, or blood disorders caused by …
be caused by accidental trauma, surgery, congenital diseases, or blood disorders caused by …
A highly efficient, in situ wet-adhesive dextran derivative sponge for rapid hemostasis
C Liu, X Liu, C Liu, N Wang, H Chen, W Yao, G Sun… - Biomaterials, 2019 - Elsevier
Uncontrolled hemorrhage is closely related to the high risk of death. However, local
hemostats still have various defects and side effects. Herein, an aldehyde dextran (PDA) …
hemostats still have various defects and side effects. Herein, an aldehyde dextran (PDA) …
Cerebral complications of snakebite envenoming: case studies
YK Huang, YC Chen, CC Liu, HC Cheng, AT Tu… - Toxins, 2022 - mdpi.com
There are an estimated 5.4 million snakebite cases every year. People with snakebite
envenoming suffer from severe complications, or even death. Although some review articles …
envenoming suffer from severe complications, or even death. Although some review articles …
Therapeutic applications of snake venoms: An invaluable potential of new drug candidates
R Diniz-Sousa, CAS Caldeira, SS Pereira… - International Journal of …, 2023 - Elsevier
Animal venoms and their chemical compounds have aroused both empirical and scientific
attention for ages. However, there has been a significant increase in scientific investigations …
attention for ages. However, there has been a significant increase in scientific investigations …
Polysaccharide-based hemostats: recent developments, challenges, and future perspectives
SS Biranje, J Sun, Y Shi, S Yu, H Jiao, M Zhang… - Cellulose, 2021 - Springer
Excessive hemorrhage is a leading cause of death to trauma patients, especially in combat
and civilian accidents. The main priority in the medical treatment of trauma patients is to …
and civilian accidents. The main priority in the medical treatment of trauma patients is to …
Nanofibrous snake venom hemostat
Controlling perioperative bleeding is of critical importance to minimize hemorrhaging and
fatality. Patients on anticoagulant therapy such as heparin have diminished clotting potential …
fatality. Patients on anticoagulant therapy such as heparin have diminished clotting potential …
Functional improvement of hemostatic dressing by addition of recombinant batroxobin
GM Seon, MH Lee, BJ Kwon, MS Kim, MA Koo, D Kim… - Acta biomaterialia, 2017 - Elsevier
Although a number of natural materials have been used as hemostatic agents, many
substances do not act quickly enough. Here, we created a novel dressings using collagen …
substances do not act quickly enough. Here, we created a novel dressings using collagen …
Development of carboxymethyl cellulose nonwoven sheet as a novel hemostatic agent
S Ohta, T Nishiyama, M Sakoda, K Machioka… - Journal of bioscience …, 2015 - Elsevier
Carboxymethyl cellulose (CMC) is a plant-derived material that has high biocompatibility
and water solubility. We developed a CMC nonwoven sheet as a hemostatic agent by …
and water solubility. We developed a CMC nonwoven sheet as a hemostatic agent by …
Elucidating the degradation mechanism of a self-degradable dextran-based medical adhesive
W Hyon, S Shibata, E Ozaki, M Fujimura, SH Hyon… - Carbohydrate …, 2022 - Elsevier
We developed a self-degradable medical adhesive, LYDEX, consisting of periodate-
oxidized aldehyde-functionalized dextran (AD) and succinic anhydride-treated ε-poly-l …
oxidized aldehyde-functionalized dextran (AD) and succinic anhydride-treated ε-poly-l …