The acute respiratory distress syndrome (ARDS) is a form of severe hypoxemic respiratory
failure that is characterized by inflammatory injury to the alveolar capillary barrier, with …

Gelatinases are members of the matrix metalloproteinase (MMPs) family; they play an
important role in the degradation of the extracellular matrix (ECM). This effect is also crucial …

Control over the Na, K-ATPase function plays a central role in adaptation of the organisms to
hypoxic and anoxic conditions. As the enzyme itself does not possess O2 binding sites its …

The cellular uptake of many nutrients and micronutrients governs both their cellular
availability and their systemic homeostasis. The cellular rate of nutrient or ion uptake (eg …

The host innate immune response, including the production of type-I IFN, represents the
primary line of defense against invading viral pathogens. Of the hundreds of IFN-stimulated …

Disruption of the alveolar–capillary barrier and accumulation of pulmonary edema, if not
resolved, result in poor alveolar gas exchange leading to hypoxia and hypercapnia, which …

Background Gold nanoparticles (GNPs) can potentially be used in biomedical fields ranging
from therapeutics to diagnostics, and their use will result in increased human exposure …

The large yellow croaker (Larimichthys crocea) is an economically important fish farmed
along the southeast coasts of China. In recent years, however, hypoxia has caused …

Organisms have evolved adaptive mechanisms in response to stress for cellular survival.
During acute hypoxic stress, cells down-regulate energy-consuming enzymes such as Na, K …

Our previous findings suggested that reversible thiol modifications of cysteine residues
within the actuator (AD) and nucleotide binding domain (NBD) of the Na, K-ATPase may …