Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …

Background and Purpose The traditional Chinese medicine, diosgenin (Dio), has attracted
increasing attention because it possesses various therapeutic effects, including anti-tumor …

Background: Ternary solid dispersions have been demonstrated to be an effective strategy
in the improvement of drug absorption and bioavailability. Method: The applications of the …

The purpose of this research was to evaluate the effect of the HPC (hydroxypropylcellulose)
and Tween 80 on the physicochemical properties and oral bioavailability of ezetimibe …

Although vaginal films were initially developed for a fast release of the drug, with the
adequate formulation they can also be useful for sustained release. The latest strategies for …

The aim of the present study was to formulate a nanosuspension (FA-NS) of fusidic acid (FA)
to enhance its aqueous solubility and antibacterial activity. The nanosuspension was …

The purpose of this work was to investigate the application of different advanced continuous
processing techniques (hot melt extrusion and spray drying) to the production of fixed-dose …

The present work reports a novel antibacterial nanocomposite film comprising of copper
nanowire impregnated biocompatible hypromellose using polyethylene glycol as a …

Solid dispersions are a useful approach to improve the dissolution rate and bioavailability of
poorly water-soluble active pharmaceutical ingredients (APIs). The aim of this study was to …

This work evaluates several compositions of an amorphous solid dispersion (ASD)
comprising nimodipine (NMD) as poorly soluble model API in a dual-polymer carrier system …