Metformin for treatment of acute COVID-19: systematic review of clinical trial data against SARS-CoV-2

SM Erickson, SL Fenno, N Barzilai, G Kuchel… - Diabetes …, 2023 - Am Diabetes Assoc
BACKGROUND Observational and preclinical data suggest metformin may prevent severe
coronavirus disease 2019 (COVID-19) outcomes. PURPOSE We conducted a systematic …

Old drug, new tricks: the utility of metformin in infection and vaccination responses to influenza and SARS-CoV-2 in older adults

DE Martin, AN Cadar, JM Bartley - Frontiers in Aging, 2023 - frontiersin.org
In the face of global pathogens such as influenza (flu) and severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), strategies beyond standard vaccines and virus …

Prevalent Metformin Use in Adults With Diabetes and the Incidence of Long COVID: An EHR-Based Cohort Study From the RECOVER Program

SG Johnson, S Abedian, T Stürmer, JD Huling… - Diabetes …, 2024 - diabetesjournals.org
OBJECTIVE Studies show metformin use before and during SARS-CoV-2 infection reduces
severe COVID-19 and postacute sequelae of SARS-CoV-2 (PASC) in adults. Our objective …

Risk of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) Among Patients with Type 2 Diabetes Mellitus on Anti-Hyperglycemic Medications

O Olawore, LE Turner, MD Evans… - Clinical …, 2024 - Taylor & Francis
Background Observed activity of metformin in reducing the risk of severe COVID-19
suggests a potential use of the anti-hyperglycemic in the prevention of post-acute sequelae …