Animal models for examining human breast cancer (HBC) carcinogenesis have been
extensively studied and proposed. With the recent advent of immunotherapy, significant …

Cancer is a common problem in dogs and although all breeds of dog and crossbred dogs
may be affected, it is notable that some breeds of pedigree dogs appear to be at increased …

Animal models refers to the animal experimental objects and related materials that can
simulate human body established in medical research. As the second-largest disease in …

Despite extensive research over many decades, human breast cancer remains a major
worldwide health concern. Advances in pre-clinical and clinical research has led to …

The enormous biologic complexity of human cancer has stimulated the development of more
appropriate experimental models that could resemble in a natural and spontaneous manner …

Spontaneous cancers in client-owned dogs closely recapitulate their human counterparts
with respect to clinical presentation, histological features, molecular profiles, and response …

Purpose Dogs have been proposed as spontaneous animal models of human breast
cancer, based on clinicopathologic similarities between canine and human mammary …

Clinical and molecular similarities between canine mammary tumours and human breast
cancer have been described in recent decades. Clinically, the similarities are very strong …

orders. A review of this topic in companion animals was published in 1991. 22 That article
marked the beginning for investigations into the potential benefits of omega-3 fatty acids in …

Purpose Relevant animal models of human breast cancer are currently needed, especially
for the aggressive triple-negative breast cancer subtype. Recent studies and our results …