Receptors for purines and pyrimidines
V Ralevic, G Burnstock - Pharmacological reviews, 1998 - ASPET
Extracellular purines (adenosine, ADP, and ATP) and pyrimidines (UDP and UTP) are
important signaling molecules that mediate diverse biological effects via cellsurface …
important signaling molecules that mediate diverse biological effects via cellsurface …
Pharmacology and structure of P2Y receptors
I von Kügelgen, K Hoffmann - Neuropharmacology, 2016 - Elsevier
Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …
Nucleotide receptors: an emerging family of regulatory molecules in blood cells
F Di Virgilio, P Chiozzi, D Ferrari… - Blood, The Journal …, 2001 - ashpublications.org
Nucleotides are emerging as an ubiquitous family of extracellular signaling molecules. It has
been known for many years that adenosine diphosphate is a potent platelet aggregating …
been known for many years that adenosine diphosphate is a potent platelet aggregating …
Pharmacological profiles of cloned mammalian P2Y-receptor subtypes
I von Kügelgen - Pharmacology & therapeutics, 2006 - Elsevier
Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …
Molecular pharmacology of P2Y-receptors
I von Kügelgen, A Wetter - Naunyn-Schmiedeberg's archives of …, 2000 - Springer
Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …
Nucleotide receptors
RA North, EA Barnard - Current opinion in neurobiology, 1997 - Elsevier
Adenosine 5′-triphosphate (ATP) and/or related nucleotides act at both ionotrophic (P2X)
and metabotropic (P2Y) receptors. P2X receptors subunits (P2X1—P2X7) form ligand-gated …
and metabotropic (P2Y) receptors. P2X receptors subunits (P2X1—P2X7) form ligand-gated …
Pharmacology of P2Y receptors
I von Kügelgen - Brain research bulletin, 2019 - Elsevier
Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …
nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …
Molecular pharmacology, physiology, and structure of the P2Y receptors
I von Kügelgen, TK Harden - Advances in pharmacology, 2011 - Elsevier
The P2Y receptors are a widely expressed group of eight nucleotide-activated G protein-
coupled receptors (GPCRs). The P2Y 1 (ADP), P2Y 2 (ATP/UTP), P2Y 4 (UTP), P2Y 6 …
coupled receptors (GPCRs). The P2Y 1 (ADP), P2Y 2 (ATP/UTP), P2Y 4 (UTP), P2Y 6 …
A human tissue‐engineered vascular media: a new model for pharmacological studies of contractile responses
N L'HEUREUX, JC STOCLET, FA AUGER… - The FASEB …, 2001 - Wiley Online Library
Our method for producing tissue‐engineered blood vessels based exclusively on the use of
human cells, ie, without artificial scaffolding, has previously been described (1). In this …
human cells, ie, without artificial scaffolding, has previously been described (1). In this …
The regulation of vascular function by P2 receptors: multiple sites and multiple receptors
MR Boarder, SMO Hourani - Trends in pharmacological sciences, 1998 - cell.com
Although the effects of nucleotides in the cardiovascular system have been known for almost
70 years, it is only in the past few years that some of the P2 receptors at which they act have …
70 years, it is only in the past few years that some of the P2 receptors at which they act have …