Global populations are undergoing a major epidemiological transition in which the burden of
atherosclerotic cardiovascular diseases is shifting rapidly from high-income to low-income …

Background Macrolide antibiotics (macrolides) are among the most commonly prescribed
antibiotics worldwide and are used for a wide range of infections. However, macrolides also …

Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of
which can produce disease in humans of all ages and can affect both pulmonary and …

Study question What is the association between clarithromycin use and cardiovascular
outcomes? Methods In this population based study the authors compared cardiovascular …

Objective To study the association of clarithromycin with cardiovascular events in the setting
of acute exacerbations of chronic obstructive pulmonary disease and community acquired …

(and possibly intermittent) level, or produce an abortive infection (see below). Alternatively,
they can be delivered to the vessel wall by circulating monocytes, which can be infected by …

Background Through several observational and mechanistic studies, microbial infection is
known to promote cardiovascular disease. Direct infection of the vessel wall, along with the …

Background The CLARICOR trial reported that clarithromycin compared with placebo
increased all-cause mortality in patients with stable coronary heart disease. This study …

Background While statins may have anti-inflammatory effects, anti-oxidative effects are
controversial. We investigated if statin treatment is associated with differences in oxidatively …

This review aims to clarify the underlying risk of arrhythmia associated with the use of
macrolides and fluoroquinolones antibiotics. Torsades de pointes (TdP) is a rare potential …