Osteomyelitis is an inflammatory bone disease that is caused by an infecting microorganism
and leads to progressive bone destruction and loss. The most common causative species …

Copper is an essential trace element required for human life, and is involved in several
physiological mechanisms. Today researchers have found and confirmed that Cu has …

Osteomyelitis is a destructive disease of bone tissue caused by infection with pathogenic
microorganisms. Because of the complex and long‐term abnormal conditions, osteomyelitis …

Osteomyelitis, or inflammation of bone, is most commonly caused by invasion of bacterial
pathogens into the skeleton. Bacterial osteomyelitis is notoriously difficult to treat, in part …

The bone infection osteomyelitis (typically by Staphylococcus aureus) usually requires a
multistep procedure of surgical debridement, long-term systemic high-dose antibiotics, and …

Staphylococcus aureus is a highly successful Gram-positive pathogen capable of causing
both superficial and invasive, life-threatening diseases. Of the invasive disease …

Osteomyelitis is an infection of the bone. Several major syndromes are commonly seen,
including hematogenous osteomyelitis, vertebral osteomyelitis (discussed elsewhere in this …

Bone defects caused by trauma or pathological events are major clinical and socioeconomic
burdens. Thus, the efforts of regenerative medicine have been focused on the development …

This review article summarizes the recent advances in pathogenic mechanisms and novel
therapeutic strategies for osteomyelitis, covering both periprosthetic joint infections and …

Abstract Purpose of Review Staphylococcus aureus is the primary pathogen responsible for
osteomyelitis, which remains a major healthcare burden. To understand its dominance, here …