Heart valves are dynamic structures that, in the average human, open and close over
100,000 times per day, and 3× 109 times per lifetime to maintain unidirectional blood flow …

The mitral valve (MV) is the left atrioventricular heart valve that regulates blood flow between
the left atrium and left ventricle (LV) during the cardiac cycle. Contrary to the aortic valve …

The tricuspid valve ensures unidirectional blood flow from the right atrium to the right
ventricle. The three tricuspid leaflets operate within a dynamic stress environment of shear …

Assessment of mitral valve (MV) function is important in many diagnostic, prognostic, and
surgical planning applications for treatment of MV disease. Yet, to date, there are no …

The complicated interaction between a fluid flow and a deformable structure is referred to as
fluid–structure interaction (FSI). FSI plays a crucial role in the functioning of the aortic valve …

Ischemic mitral regurgitation (IMR) is a prevalent cardiac disease associated with substantial
morbidity and mortality. Contemporary surgical treatments continue to have limited long-term …

Ischemic mitral regurgitation (IMR) is a currently prevalent disease in the US that is projected
to become increasingly common as the aging population grows. In recent years, image …

Cell-shape is a conglomerate of mechanical, chemical, and biological mechanisms that
reflects the cell biophysical state. In a specific application, we consider aortic valve interstitial …

Abstract Each year, more than 40,000 people undergo mitral valve (MV) repair surgery
domestically to treat regurgitation caused by myocardial infarction (MI). Although continual …

Ischaemic mitral regurgitation (IMR), a frequent complication following myocardial infarction
(MI), leads to higher mortality and poor clinical prognosis if untreated. Accumulating …