Glutathione is a tripeptide that plays a pivotal role in critical physiological processes
resulting in effects relevant to diverse disease pathophysiology such as maintenance of …

Glucosinolates and isothiocyanates have both been objects of research for more than half a
century. Interest in these unique phytochemicals escalated following the discovery that …

Background Since the re-discovery of sulforaphane in 1992 and the recognition of the
bioactivity of this phytochemical, many studies have examined its mode of action in cells …

Research into human biotransformation and elimination systems continues to evolve.
Various clinical and in vivo studies have been undertaken to evaluate the effects of foods …

The epidemiological evidence suggests a strong inverse relationship between dietary intake
of cruciferous vegetables and the incidence of cancer. Among other constituents of …

Background Epidemiological evidence suggests that consumption of cruciferous vegetables
is associated with reduced risk of prostate cancer progression, largely attributed to the …

A high consumption of vegetables belonging to the Brassicaceae family has been related to
a lower incidence of chronic diseases including different kinds of cancer. These beneficial …

Isothiocyanates (ITC), derived from glucosinolates, are thought to be responsible for the
chemoprotective actions conferred by higher cruciferous vegetable intake. Evidence …

The rise in noncommunicable chronic diseases associated with changing diet and lifestyles
throughout the world is a major challenge for society. It is possible that certain dietary …

The isothiocyanate (ITC) sulforaphane (SFN) was shown at low levels (1–5 µM) to promote
cell proliferation to 120–143% of the controls in a number of human cell lines, whilst at high …