1. INTRODUCTION Bicyclic oxygen heterocycles resulting from fusion of benzene ring with
5, 6-positions of either 2H-or 4H-pyran ring system are designated as 2H-chromene (2H-1 …

Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Ethnopharmacological relevance Piperaceae is the fifth largest family of plants in Panama.
This review focuses on the ethnomedical uses of the most prevalent Panamanian species …

Infectious diseases caused by parasites are a major threat for the entire mankind, especially
in the tropics. More than 1 billion people world-wide are directly exposed to tropical …

Background The two available drugs for treatment of T. cruzi infection, nifurtimox and
benznidazole (BZ), have potential toxic side effects and variable efficacy, contributing to their …

A convenient, one‐pot multi‐component methodology was developed for the preparation of
tetrahydro‐4H‐chromene and dihydropyrano [c] chromene derivatives as important …

We describe herein an evaluation of the trypanocidal effect of eight piperamides (1–8)
isolated from Piper tuberculatum bearing dihydropyridone, piperidine, and isobutyl moieties …

In this work, agro‐waste stuff was employed as a natural source catalyst for the synthesis of
2‐amino‐4H‐chromene as green protocol. The synthesis was carried out in three …

BACKGROUND Recent studies showed that essential oils from different pepper species
(Piper spp.) have promising leishmanicidal and trypanocidal activities. OBJECTIVES In …

Abstract 2H-Pyran-2-ones are widely present in nature and found as either isolated or in
fused form. Depending on the fusion of benzene ring, pyran can give coumarins …