Sepsis is a syndrome characterized by life-threatening organ dysfunction caused by the
dysregulated host response to an infection. Sepsis, especially septic shock and multiple …

Sepsis is a complex syndrome characterized by multi-organ dysfunction, due to the
presence of harmful microorganisms in blood which could cause mortality. Complications …

Background Patients with severe mental illness (SMI)(ie, schizophrenia, bipolar disorder, or
major depressive disorder) have been reported to have excess mortality rates from infection …

Background Observational studies have indicated a potential association between
autoimmune diseases and the occurrence of sepsis, with an increased risk of mortality …

Acute kidney injury (AKI) occurs in half of patients with septic shock, resulting in
unacceptably high mortality. However, effective preventive treatments are still lacking. We …

Background Except in a few retrospective studies mainly including patients under
chemotherapy, information regarding the impact of immunosuppressive therapy on the …

Background Mental disorders are associated with markedly reduced life expectancy, in part
due to an increased risk of death due to infection, likely reflecting sepsis-associated …

Background The prevalence of persistent inflammation, immunosuppression, and
catabolism syndrome (PICS) has an upward trend in sepsis patients and can be associated …

(1) Background: Sepsis is a leading cause of death and a global public health problem.
Accordingly, deciphering the underlying molecular mechanisms of this disease and the …

Introduction/Background: Patients with rheumatoid arthritis (RA) have a high risk of
infections that may require intensive care unit (ICU) admission in case of resulting sepsis …