Expanded HILUS trial: a pooled analysis of risk factors for toxicity from stereotactic body radiation therapy of central and ultracentral lung tumors
S Lindberg, V Grozman, K Karlsson, E Onjukka… - International Journal of …, 2023 - Elsevier
Purpose Stereotactic body radiation therapy for tumors near the central airways implies high-
grade toxic effects, as concluded from the HILUS trial. However, the small sample size and …
grade toxic effects, as concluded from the HILUS trial. However, the small sample size and …
To fly or not to fly: Stereotactic MR-guided adaptive radiotherapy effectively treats ultracentral lung tumors with favorable long-term outcomes
S Regnery, E Katsigiannopulos, P Hoegen… - Lung Cancer, 2023 - Elsevier
Background Stereotactic radiotherapy of ultracentral lung tumors (ULT) is challenging as it
may cause overdoses to sensitive mediastinal organs with severe complications. We aimed …
may cause overdoses to sensitive mediastinal organs with severe complications. We aimed …
Outcome of conventional radiotherapy in small centrally located tumours or lymph nodes: minimal toxicity, remarkable survival but challenging loco-regional control
Background In peripheral lung tumours, stereotactic body radiotherapy (SBRT) is superior to
conventional RT. SBRT has also shown high loco-regional control (LC) in centrally located …
conventional RT. SBRT has also shown high loco-regional control (LC) in centrally located …
Stereotactic radiotherapy for ultracentral lung tumours
V Bourbonne, S Thureau, O Pradier, D Antoni… - Cancer …, 2023 - Elsevier
Ultracentral (UC) lung lesions are generally defined by the presence of the tumour or the
Planning Target Volume (PTV) abutting proximal bronchial tree (PBT) or the esophagus …
Planning Target Volume (PTV) abutting proximal bronchial tree (PBT) or the esophagus …
Balancing tumour control probability and toxicity in SBRT of ultra-central lung tumours–One step forward
K Lindberg - Lung Cancer, 2023 - lungcancerjournal.info
Stereotactic body radiation therapy (SBRT) of centrally located lung tumours is challenging,
given the risk of high-grade toxic effects for patients with a short tumour-bronchial distance …
given the risk of high-grade toxic effects for patients with a short tumour-bronchial distance …
Stereotactic body radiotherapy for centrally located inoperable early-stage NSCLC: EORTC 22113-08113 LungTech phase II trial results
A Levy, S Adebahr, C Hurkmans, M Ahmed… - Journal of Thoracic …, 2024 - Elsevier
Background The international EORTC phase II single-arm LungTech trial 22113-08113
assessed safety and efficacy of stereotactic body radiotherapy (SBRT) in patients with …
assessed safety and efficacy of stereotactic body radiotherapy (SBRT) in patients with …
Quantitative assessment of dosimetric effect of using alternative OAR delineations in treatment planning as functions of delineations, setup uncertainty and planning …
MNH Rashad, A Karki, J Czak, VG Alves… - arXiv preprint arXiv …, 2024 - arxiv.org
Purpose: This study aims to quantify the variation in dose-volume histogram (DVH) and
normal tissue complication probability (NTCP) metrics for head-and-neck (HN) cancer …
normal tissue complication probability (NTCP) metrics for head-and-neck (HN) cancer …
Lung tumors
The modern evolution in radiotherapy is highly dependent on the continuous introduction of
novel technologies that facilitate modulation of the tumor and normal tissue differential …
novel technologies that facilitate modulation of the tumor and normal tissue differential …
Radiotherapy dosimetry at multiple levels to improve precision, development and understanding of treatment
New techniques and technologies are continuously emerging and developing in radiation
oncology. The ongoing aim of much physics-based research is to improve the overall …
oncology. The ongoing aim of much physics-based research is to improve the overall …
Beyond the HILUS Trial: How Can We Improve the Safety of SABR for Ultracentral Thoracic Tumors?
AH Safavi, DA Palma, ME Giuliani - International Journal of …, 2023 - redjournal.org
SABR for ultracentral thoracic tumors is a double-edged sword: it affords the opportunity to
aggressively control inevitably morbid, often unresectable disease abutting the central …
aggressively control inevitably morbid, often unresectable disease abutting the central …