Tracing skin aging process: A mini-review of in vitro approaches

S Letsiou - Biogerontology, 2021 - Springer
Skin is a rather complex, yet useful organ of our body. Besides, skin aging is a complicated
process that gains a growing interest as mediates many molecular processes in our body …

Advances in Skin-Mimetic Platforms: A Comprehensive Review of Drug Permeation Models

D Suthar, R Raut, A Bajaj - Journal of Drug Delivery Science and …, 2024 - Elsevier
In recent days, the utilization of the skin as a pathway for drug delivery has gained
substantial popularity and recognition. The skin's natural barrier properties pose a significant …

Residual antimicrobial effect of chlorhexidine digluconate and octenidine dihydrochloride on reconstructed human epidermis

G Müller, J Langer, J Siebert, A Kramer - Skin pharmacology and …, 2013 - karger.com
The objective of the present investigation was to examine the residual antimicrobial activity
after a topical exposure of reconstructed human epidermis (RHE) to equimolar solutions of …

Comparison of structure and organization of cutaneous lipids in a reconstructed skin model and human skin: spectroscopic imaging and chromatographic profiling

A Tfayli, F Bonnier, Z Farhane, D Libong… - Experimental …, 2014 - Wiley Online Library
The use of animals for scientific research is increasingly restricted by legislation, increasing
the demand for human skin models. These constructs present comparable bulk lipid content …

Assessment of the optimized SkinEthic™ Reconstructed Human Epidermis (RHE) 42 bis skin irritation protocol over 39 test substances

C Tornier, C Amsellem, AB de Fraissinette, N Alépée - Toxicology in vitro, 2010 - Elsevier
The development of in vitro protocols able to discriminate skin irritants from non-irritants
integrates the toxicologists' needs for reliable and robust in vitro tools for screening test …

[HTML][HTML] Cholesterol sulfate and Ca2+ modulate the mixing properties of lipids in stratum corneum model mixtures

M Arseneault, M Lafleur - Biophysical journal, 2007 - cell.com
The influence of cholesterol sulfate (CS) and calcium on the phase behavior of lipid mixtures
mimicking the stratum corneum (SC) lipids was examined using vibrational spectroscopy …

[HTML][HTML] In vitro investigation of metabolic fate of α-mangostin and gartanin via skin permeation by LC-MS/MS and in silico evaluation of the metabolites by ADMET …

P Rukthong, N Sereesongsang, T Kulsirirat… - … medicine and therapies, 2020 - Springer
Abstract Background Mangosteen, Garciniam angostana L., is a juicy fruit commonly found
in Thailand. The rinds of Garciniam angostana L. have been used as a traditional medicine …

The skin barrier function: a micro‐PIXE study

M Simon, P Barberet, P Moretto… - X‐Ray Spectrometry …, 2009 - Wiley Online Library
Human body is perpetually subjected to environmental exposures as sun, natural, urban or
industrial pollutions and societal exposures. Skin is the main physiological barrier facing to …

Aplicação tópica de bioflavonóides em epiderme humana reconstruída in vitro usando nanopartículas lipídicas

RL Santos - 2023 - repositorio.ul.pt
A quercetina (QT) é um flavonóide com diversas atividades terapêuticas atribuídas
principalmente às suas capacidades antioxidante, anti-inflamatória, anticancerígena …

Mathematical models of calcium and tight junctions in normal and reconstructed epidermis

MP Adams - Bulletin of the Australian Mathematical Society, 2016 - cambridge.org
The epidermis is the uppermost layer of the skin. It possesses a distinct stratified structure
consisting of four sublayers and a characteristic calcium profile which is strongly implicated …