[HTML][HTML] Deep brain stimulation: a review of the open neural engineering challenges
Objective. Deep brain stimulation (DBS) is an established and valid therapy for a variety of
pathological conditions ranging from motor to cognitive disorders. Still, much of the DBS …
pathological conditions ranging from motor to cognitive disorders. Still, much of the DBS …
[HTML][HTML] Past, present, and future of deep brain stimulation: hardware, software, imaging, physiology and novel approaches
Deep brain stimulation (DBS) has advanced treatment options for a variety of neurologic and
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …
[HTML][HTML] Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …
families, the search for new therapies has been a source of hope and frustration. Almost all …
[HTML][HTML] Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia
LN Miterko, T Lin, J Zhou, ME van der Heijden… - Nature …, 2021 - nature.com
Deep brain stimulation (DBS) relieves motor dysfunction in Parkinson's disease, and other
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …
[HTML][HTML] Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters
Background Electrical neuromodulation via direct electrical stimulation (DES) is an
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …
StimFit—a data‐driven algorithm for automated deep brain stimulation programming
J Roediger, TA Dembek, G Wenzel… - Movement …, 2022 - Wiley Online Library
Background Finding the optimal deep brain stimulation (DBS) parameters from a multitude
of possible combinations by trial and error is time consuming and requires highly trained …
of possible combinations by trial and error is time consuming and requires highly trained …
Structuro-functional surrogates of response to subcallosal cingulate deep brain stimulation for depression
Subcallosal cingulate deep brain stimulation produces long-term clinical improvement in
approximately half of patients with severe treatment-resistant depression. We hypothesized …
approximately half of patients with severe treatment-resistant depression. We hypothesized …
Metabolic activity in subcallosal cingulate predicts response to deep brain stimulation for depression
Subcallosal cingulate (SCC) deep brain stimulation (DBS) is a promising therapy for
treatment-resistant depression (TRD), but response rates in open-label studies were not …
treatment-resistant depression (TRD), but response rates in open-label studies were not …
Long versus short pulse width subcallosal cingulate stimulation for treatment-resistant depression: a randomised, double-blind, crossover trial
R Ramasubbu, DL Clark, S Golding… - The Lancet …, 2020 - thelancet.com
Background Stimulation adjustment is required to optimise outcomes of deep brain
stimulation (DBS) for treatment-resistant depression, but controlled data for ideal stimulation …
stimulation (DBS) for treatment-resistant depression, but controlled data for ideal stimulation …
A review of neurophysiological effects and efficiency of waveform parameters in deep brain stimulation
Neurostimulation has diverse clinical applications and potential as a treatment for medically
refractory movement disorders, epilepsy, and other neurological disorders. However, the …
refractory movement disorders, epilepsy, and other neurological disorders. However, the …