Motivational and motor deficits are common in patients with depression and other psychiatric
disorders, and are related to symptoms of anhedonia and motor retardation. These deficits in …

Schizophrenia is associated with abnormalities of hippocampal structure and function.
Neuroimaging studies have shown that the hippocampus is hyperactive in schizophrenia …

This book reviews how people and animals learn and how their behaviors are later changed
as a result of this learning. Nearly all of our behaviors are influenced by prior learning …

Genomic studies have identified hundreds of candidate genes near loci associated with risk
for schizophrenia. To define candidates and their functions, we mutated zebrafish orthologs …

Abnormalities in the simplest form of learning, habituation, have been reported in a variety of
neuropsychiatric disorders as etiologically diverse as Autism Spectrum Disorder, Fragile X …

Schizophrenia is a grave neuropsychiatric disease which frequently onsets between the end
of adolescence and the beginning of adulthood. It is characterized by a variety of …

Recent work indicates that there are distinct response habituation mechanisms that can be
recruited by different stimulation rates and that can underlie different components (eg, the …

The normal brain development and function are delicately driven by an ever-changing
milieu of steroid hormones arising from fetal, placental, and maternal origins. This reliance …

The development of current neuroleptics was largely aiming to decrease excessive
dopaminergic signaling in the striatum. However, the notion that abnormal dopamine …

Schizophrenia is a severe disorder characterized by positive, negative and cognitive
symptoms, which are still not fully understood. The development of efficient antipsychotics …