Aminoglycoside uptake, stress, and potentiation in Gram-negative bacteria: new therapies with old molecules

M Lang, A Carvalho, Z Baharoglu… - … and Molecular Biology …, 2023 - Am Soc Microbiol
Aminoglycosides (AGs) are long-known molecules successfully used against Gram-negative
pathogens. While their use declined with the discovery of new antibiotics, they are now …

Biofilm antimicrobial susceptibility through an experimental evolutionary lens

T Coenye, M Bové, T Bjarnsholt - NPJ biofilms and microbiomes, 2022 - nature.com
Experimental evolution experiments in which bacterial populations are repeatedly exposed
to an antimicrobial treatment, and examination of the genotype and phenotype of the …

[HTML][HTML] The Role of Stakeholders' Understandings in Emerging Antimicrobial Resistance: A One Health Approach

P Nardulli, A Ballini, M Zamparella, D De Vito - Microorganisms, 2023 - mdpi.com
The increasing misuse of antibiotics in human and veterinary medicine and in
agroecosystems and the consequent selective pressure of resistant strains lead to multidrug …

Layer-by-layer designer nanoarchitectonics for physical and chemical communications in functional materials

K Ariga, J Song, K Kawakami - Chemical Communications, 2024 - pubs.rsc.org
Nanoarchitectonics, as a post-nanotechnology concept, constructs functional materials and
structures using nanounits of atoms, molecules, and nanomaterials as materials. With the …

Bacterial Persister Cells and Development of Antibiotic Resistance in Chronic Infections: An Update

AP Kunnath, M Suodha Suoodh… - British Journal of …, 2024 - frontierspartnerships.org
The global issue of antimicrobial resistance poses significant challenges to public health.
The World Health Organization (WHO) has highlighted it as a major global health threat …

A 'rich-get-richer'mechanism drives patchy dynamics and resistance evolution in antibiotic-treated bacteria

E Şimşek, K Kim, J Lu, A Silver, N Luo… - Molecular Systems …, 2024 - embopress.org
Bacteria in nature often form surface-attached communities that initially comprise distinct
subpopulations, or patches. For pathogens, these patches can form at infection sites, persist …

In vivo evolution of antimicrobial resistance in a biofilm model of Pseudomonas aeruginosa lung infection

D Higazy, AD Pham, C van Hasselt, N Høiby… - The ISME …, 2024 - academic.oup.com
The evolution of antimicrobial resistance (AMR) in biofilms has been repeatedly studied by
experimental evolution in vitro, but rarely in vivo. The complex microenvironment at the …

[HTML][HTML] In vitro models for studying implant-associated biofilms-A review from the perspective of bioengineering 3D microenvironments

S Cometta, DW Hutmacher, L Chai - Biomaterials, 2024 - Elsevier
Biofilm research has grown exponentially over the last decades, arguably due to their
contribution to hospital acquired infections when they form on foreign body surfaces such as …

Protective effects of antibiotic resistant bacteria on susceptibles in biofilm: Influential factors, mechanism, and modeling

F Xu, M Jiang, D Li, P Yu, H Ma, H Lu - Science of The Total Environment, 2024 - Elsevier
In environmental biofilms, antibiotic-resistant bacteria facilitate the persistence of susceptible
counterparts under antibiotic stresses, contributing to increased community-level resistance …

Polyhexamethylene biguanide promotes adaptive cross-resistance to gentamicin in Escherichia coli biofilms

R Charron, P Lemée, A Huguet, O Minlong… - Frontiers in Cellular …, 2023 - frontiersin.org
Antimicrobial resistance is a critical public health issue that requires a thorough
understanding of the factors that influence the selection and spread of antibiotic-resistant …