Ethnomedicinal values of Boerhaavia diffusa L. as a panacea against multiple human ailments: a state of art review

S Das, PK Singh, S Ameeruddin… - Frontiers in …, 2023 - frontiersin.org
Ethnopharmacological relevance: Therapeutic botanicals (plants and derivatives) are in use
since antiquity for various health ailments. The ethnic community is the repository of the …

An overview on arsenic trioxide-induced cardiotoxicity

VP Vineetha, KG Raghu - Cardiovascular Toxicology, 2019 - Springer
Arsenic trioxide (ATO) is among the first-line chemotherapeutic drugs used in oncological
practice. It has shown substantial efficacy in treating patients with relapsed or refractory …

[HTML][HTML] H9c2 and HL-1 cells demonstrate distinct features of energy metabolism, mitochondrial function and sensitivity to hypoxia-reoxygenation

AV Kuznetsov, S Javadov, S Sickinger… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Dysfunction of cardiac energy metabolism plays a critical role in many cardiac diseases,
including heart failure, myocardial infarction and ischemia–reperfusion injury and organ …

Selenium mitigated aflatoxin B1-induced cardiotoxicity with potential regulation of 4 selenoproteins and ferroptosis signaling in chicks

L Zhao, Y Feng, ZJ Xu, NY Zhang, WP Zhang… - Food and Chemical …, 2021 - Elsevier
The aim of the present study was to explore the underlying mechanism of selenium (Se)-
mediated detoxification of aflatoxin B 1 (AFB 1)-induced cardiotoxicity in chicks. A Se …

Mitochondrial protection by simvastatin against angiotensin II‐mediated heart failure

CC Hsieh, CY Li, CH Hsu, HL Chen… - British Journal of …, 2019 - Wiley Online Library
Background and Purpose Mitochondrial dysfunction plays a role in the progression of
cardiovascular diseases including heart failure. 3‐Hydroxy‐3‐methylglutaryl‐CoA reductase …

Exposure to zinc oxide nanoparticles (ZnO-NPs) induces cardiovascular toxicity and exacerbates pathogenesis–Role of oxidative stress and MAPK signaling

M Nagarajan, GB Maadurshni, GK Tharani… - Chemico-Biological …, 2022 - Elsevier
The precise toxico-pathogenic effects of zinc oxide nanoparticles (ZnO-NPs) on the
cardiovascular system under normal and cardiovascular disease (CVD) risk factor milieu are …

Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress

N Jaiswal, CK Maurya, D Arha, DR Avisetti… - Apoptosis, 2015 - Springer
Mitochondrial dysfunction in skeletal muscle has been implicated in the development of
insulin resistance, a major characteristic of type 2 diabetes. There is evidence that oxidative …

A novel isoquinoline derivative anticancer agent and its targeted delivery to tumor cells using transferrin-conjugated liposomes

X Yang, S Yang, H Chai, Z Yang, RJ Lee, W Liao… - PloS one, 2015 - journals.plos.org
We have screened 11 isoquinoline derivatives and α-methylene-γ-butyrolactones using the
3-(4, 5-dimethylthi-azol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) cytotoxicity assay in …

MiR-944 functions as a novel oncogene and regulates the chemoresistance in breast cancer

H He, W Tian, H Chen, K Jiang - Tumor Biology, 2016 - Springer
MircroRNAs are emerging as critical regulators in carcinogenesis and chemoresistance in
multiple cancer types. In this study, we observed that the miR-944 level was upregulated in …

[HTML][HTML] MiR-181b promotes chemoresistance in breast cancer by regulating Bim expression

Y Zheng, X Lv, X Wang, B Wang… - Oncology …, 2016 - spandidos-publications.com
MicroRNAs are emerging as critical regulators of the initiation and progression of multiple
types of human cancers, including breast cancer. In the present study, the expression of miR …