Caffeine is a widely recognized psychostimulant compound with a long history of
consumption by humans. While it has received a significant amount of attention there is still …

The detailed understanding of the binding of small molecules to proteins is the key for the
development of novel drugs or to increase the acceptance of substrates by enzymes …

Methylxanthines (MTX) are purine derived xanthine derivatives. Whereas naturally occurring
methylxanthines like caffeine, theophylline or theobromine are widely consumed in food …

Flavonoids are a class of bioactive plant-derived natural products that exhibit a broad range
of biological activities, including antibacterial ones. Their inhibitory activity toward Gram …

Caffeine, which shares consubstantial structural similarity with purine adenosine, has been
demonstrated as a nonselective adenosine receptor antagonist for eliciting most of the …

The one-sided addition of fengycin (FE) to planar lipid bilayers mimicking target fungal cell
membranes up to 0.1 to 0.5 μM in the membrane bathing solution leads to the formation of …

The ever-faster rise of antimicrobial resistance (AMR) represents a major global Public
Health challenge. New chemical entities with innovative Modes of Action (MoAs) are thus …

Cationic lipid membranes have recently attracted huge attention both from a fundamental
point of view and due to their practical applications in drug delivery and gene therapy. The …

Biological membranes and their diverse lipid constituents play key roles in a broad spectrum
of cellular and physiological processes. Characterization of membrane-associated …

It is widely recognized that an alteration in membrane physical properties induced by the
adsorption of various drugs and biologically active compounds might greatly affect the …