[HTML][HTML] Aspergillus derived mycotoxins in food and the environment: Prevalence, detection, and toxicity

V Navale, KR Vamkudoth, S Ajmera, V Dhuri - Toxicology reports, 2021 - Elsevier
Aspergillus species are the paramount ubiquitous fungi that contaminate various food
substrates and produce biochemicals known as mycotoxins. Aflatoxins (AFTs), ochratoxin A …

Oxidative cyclization in natural product biosynthesis

MC Tang, Y Zou, K Watanabe, CT Walsh… - Chemical …, 2017 - ACS Publications
Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus

RP De Vries, R Riley, A Wiebenga, G Aguilar-Osorio… - Genome biology, 2017 - Springer
Abstract Background The fungal genus Aspergillus is of critical importance to humankind.
Species include those with industrial applications, important pathogens of humans, animals …

Photoredox-catalyzed diastereoselective dearomative prenylation and reverse-prenylation of electron-deficient indole derivatives

X Chang, F Zhang, S Zhu, Z Yang, X Feng… - Nature …, 2023 - nature.com
Prenylated and reverse-prenylated indolines are privileged scaffolds in numerous naturally
occurring indole alkaloids with a broad spectrum of important biological properties …

Prenylated indole derivatives from fungi: structure diversity, biological activities, biosynthesis and chemoenzymatic synthesis

SM Li - Natural product reports, 2010 - pubs.rsc.org
Covering: up to mid-2009 Prenylated indole alkaloids are hybrid natural products derived
from prenyl diphosphates and tryptophan or its precursors and widely distributed in …

Biosynthesis of pyrroloindoline-containing natural products

C Sun, W Tian, Z Lin, X Qu - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to 2022 Pyrroloindoline is a privileged tricyclic indoline motif widely present in
many biologically active and medicinally valuable natural products. Thus, understanding the …

The shikimate pathway: gateway to metabolic diversity

VV Shende, KD Bauman, BS Moore - Natural Product Reports, 2024 - pubs.rsc.org
Covering: 1997 to 2023 The shikimate pathway is the metabolic process responsible for the
biosynthesis of the aromatic amino acids phenylalanine, tyrosine, and tryptophan. Seven …

Advances in Aspergillus secondary metabolite research in the post-genomic era

JF Sanchez, AD Somoza, NP Keller… - Natural product reports, 2012 - pubs.rsc.org
Covering: 2005 to 2011 This review studies the impact of whole genome sequencing on
Aspergillus secondary metabolite research. There has been a proliferation of many new …

Biosynthesis of fungal indole alkaloids

W Xu, DJ Gavia, Y Tang - Natural product reports, 2014 - pubs.rsc.org
Covering: up to 2014 This review provides a summary of recent research advances in
elucidating the biosynthesis of fungal indole alkaloids. The different strategies used to …

Nature loves nitrogen heterocycles

CT Walsh - Tetrahedron Letters, 2015 - Elsevier
Nitrogen-containing heterocycles are central to the chemical reactions that occur in all
organisms. The metabolic transformation of amino acids into five, six, and seven-member …