Bacterial infections after burn injuries: impact of multidrug resistance

AM Lachiewicz, CG Hauck, DJ Weber… - Clinical Infectious …, 2017 - academic.oup.com
Patients who are admitted to the hospital after sustaining a large burn injury are at high risk
for developing hospital-associated infections. If patients survive the initial 72 hours after a …

Antifungal drugs TDM: trends and update

B Kably, M Launay, A Derobertmasure… - Therapeutic Drug …, 2022 - journals.lww.com
Purpose: The increasing burden of invasive fungal infections results in growing challenges
to antifungal (AF) therapeutic drug monitoring (TDM). This review aims to provide an …

Augmented renal clearance and how to augment antibiotic dosing

IH Chen, DP Nicolau - Antibiotics, 2020 - mdpi.com
Augmented renal clearance (ARC) refers to the state of heightened renal filtration commonly
observed in the critically ill. Its prevalence in this patient population is a consequence of the …

Multidrug‐Resistant Pathogens in Burn Wound, Prevention, Diagnosis, and Therapeutic Approaches (Conventional Antimicrobials and Nanoparticles)

J Hemmati, M Azizi, B Asghari… - Canadian Journal of …, 2023 - Wiley Online Library
Multidrug‐resistant pathogens are one of the common causes of death in burn patients and
have a high risk of nosocomial infections, especially pneumonia, urinary tract infections, and …

Management and prevention of drug resistant infections in burn patients

R Vinaik, D Barayan, S Shahrokhi… - Expert review of anti …, 2019 - Taylor & Francis
Introduction: Despite modern advances, the primary cause of death after burns remains
infection and sepsis. A key factor in determining outcomes is colonization with multi-drug …

Tissue penetration of antimicrobials in intensive care unit patients: a systematic review—part II

B Viaggi, A Cangialosi, M Langer, C Olivieri, A Gori… - Antibiotics, 2022 - mdpi.com
In patients that are admitted to intensive care units (ICUs), the clinical outcome of severe
infections depends on several factors, as well as the early administration of chemotherapies …

Antibiotics and ECMO in the Adult Population—Persistent Challenges and Practical Guides

F Gomez, J Veita, K Laudanski - Antibiotics, 2022 - mdpi.com
Extracorporeal membrane oxygenation (ECMO) is an emerging treatment modality
associated with a high frequency of antibiotic use. However, several covariables emerge …

Infections in burn patients

JL Kiley, DG Greenhalgh - Surgical Clinics, 2023 - surgical.theclinics.com
Infections are the leading cause of mortality in burn patients who survive initial resuscitation
1, 2 and present diagnostic and therapeutic challenges. 3 Here, the authors discuss the role …

The First 24 hours: Burn shock resuscitation and early complications

S Tejiram, SP Tranchina, TE Travis… - Surgical Clinics, 2023 - surgical.theclinics.com
Patients sustaining a thermal injury of 20% or greater of their total body surface area (TBSA)
will require fluid resuscitation to treat shock. 1 Those patients with TBSA injury less than …

Pharmacokinetics and pharmacodynamics of antimicrobial agents in burn patients

KA Pruskowski - Surgical Infections, 2021 - liebertpub.com
Background: Infection is common after burn injury and accounts for the most frequent
complications of burn injury. This review describes the effects of burn injury on …