Mechanistic insights for drug repurposing and the design of hybrid drugs for Alzheimer's disease

D Padhi, T Govindaraju - Journal of Medicinal Chemistry, 2022 - ACS Publications
The heterogeneity and complex nature of Alzheimer's disease (AD) is attributed to several
genetic risk factors and molecular culprits. The slow pace and increasing failure rate of …

Hypoglycemia and Alzheimer Disease Risk: The Possible Role of Dasiglucagon

NH Ali, HM Al-Kuraishy, AI Al-Gareeb, NR Hadi… - Cellular and Molecular …, 2024 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory impairment and cognitive dysfunctions. It has been shown that hypoglycemia can …

Anti-Amyloid β Aggregation Activity and Cell Viability Effect of Betacyanins from Red Pitahaya (Hylocereus polyrhizus) for Alzheimer's Disease

PN Thwe, KY Yeong, WS Choo - Plant Foods for Human Nutrition, 2023 - Springer
Betacyanin-rich extract from red beet (Beta vulgaris) was recently reported to inhibit amyloid
β (Aβ) aggregation, a main pathological event in Alzheimer's disease. However, the anti-Aβ …

Purinergic Receptor P2Y12-Mediated Tau Internalization in Microglia

H Chidambaram, SE Desale… - Tau Protein: Methods and …, 2024 - Springer
Microglia are the resident brain macrophage cells that are involved in constant surveillance
of brain microenvironment. In Alzheimer's disease, microglia get over activated upon the …

Check Chapter 25 updates

H Chidambaram, SE Desale… - Tau Protein: Methods …, 2024 - books.google.com
Microglia are the resident brain macrophage cells that are involved in constant surveillance
of brain microenvironment. In Alzheimer's disease, microglia get over activated upon the …