Rare actinomycetes are prolific in the marine environment; however, knowledge about their
diversity, distribution and biochemistry is limited. Marine rare actinomycetes represent a …

Antimicrobial resistance (AR) is recognized as one of the greatest threats to public health
and in global concern. Consequently, the increased morbidity and mortality, which are …

Submarine canyons are major geomorphic features of continental margins around the world.
Several recent multidisciplinary projects focused on the study of canyons have considerably …

The increasing emergence of new forms of multidrug resistance among human pathogenic
bacteria, coupled with the consequent increase of infectious diseases, urgently requires the …

Abstract β-Carbolines are indole alkaloids having a tricyclic pyrido [3, 4-b] indole ring in their
structure. Since the isolation of first β-carboline from Peganum harmala in 1841, the isolation …

Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …

The marine environment is a rich source of biologically active molecules for the treatment of
human diseases, especially cancer. The adaptation to unique environmental conditions led …

Who owns ocean biodiversity? This is an increasingly relevant question, given the legal
uncertainties associated with the use of genetic resources from areas beyond national …

Deep sea is a unique and extreme environment. It is a hot spot for hunting marine
actinomycetes resources and secondary metabolites. The novel deep sea actinomycete …

The microorganisms that evolved at low temperatures express cold-adapted enzymes
endowed with unique catalytic properties in comparison to their mesophilic homologues, ie …