Advances in Toxoplasma gondii Vaccines: Current Strategies and Challenges for Vaccine Development
KB Chu, FS Quan - Vaccines, 2021 - mdpi.com
Toxoplasmosis, caused by the apicomplexan parasite Toxoplasma gondii, is one of the most
damaging parasite-borne zoonotic diseases of global importance. While approximately one …
damaging parasite-borne zoonotic diseases of global importance. While approximately one …
Protective mucosal and systemic immunity induced by virus-like particles expressing Toxoplasma gondii cyst wall protein
GD Eom, KB Chu, HJ Kang, MJ Kim, KW Yoon, J Mao… - Plos one, 2023 - journals.plos.org
Toxoplasma gondii host cellular invasion factors such as the rhoptry proteins, micronemal
antigens, or other subcellular compartment proteins have shown limited vaccine efficacies …
antigens, or other subcellular compartment proteins have shown limited vaccine efficacies …
Heterologous immunization targeting the CST1 antigen confers better protection than ROP18 in mice
GD Eom, KB Chu, J Mao, KW Yoon, HJ Kang… - …, 2024 - Taylor & Francis
Aim: To evaluate the protective efficacy induced by heterologous immunization with
recombinant baculoviruses or virus-like particles targeting the CST1 and ROP18 antigens of …
recombinant baculoviruses or virus-like particles targeting the CST1 and ROP18 antigens of …
Mucosal Administration of Recombinant Baculovirus Displaying Toxoplasma gondii ROP4 Confers Protection Against T. gondii Challenge Infection in Mice
KW Yoon, KB Chu, HJ Kang, MJ Kim… - Frontiers in Cellular …, 2021 - frontiersin.org
Pathogens require physical contact with the mucosal surface of the host organism to initiate
infection and as such, vaccines eliciting both mucosal and systemic immune responses …
infection and as such, vaccines eliciting both mucosal and systemic immune responses …
[HTML][HTML] Biotechnological based recombinant protein vaccines developed against toxoplasmosis
Toxoplasma gondii (T. gondii) that can infect most warm-blooded animals and humans, is an
obligate intracellular apicomplexan parasite with a wide host range. About one-third of the …
obligate intracellular apicomplexan parasite with a wide host range. About one-third of the …
Multiple neuraminidase containing influenza virus-like particle vaccines protect mice from avian and human influenza virus infection
HJ Kang, KB Chu, KW Yoon, GD Eom, J Mao, MJ Kim… - Viruses, 2022 - mdpi.com
Avian influenza virus remains a threat for humans, and vaccines preventing both avian and
human influenza virus infections are needed. Since virus-like particles (VLPs) expressing …
human influenza virus infections are needed. Since virus-like particles (VLPs) expressing …
Protective Immunity Induced by Immunization with Baculovirus, Virus-like Particle, and Vaccinia Virus Expressing the AMA1 of Plasmodium berghei
MJ Kim, KB Chu, HJ Kang, KW Yoon, GD Eom, J Mao… - Biomedicines, 2022 - mdpi.com
Heterologous prime–boost immunization regimens using various vaccine platforms
demonstrated promising results against infectious diseases. Here, mice were sequentially …
demonstrated promising results against infectious diseases. Here, mice were sequentially …
Toward innovative veterinary nanoparticle vaccines
M Sun, AC Pratama, H Qiu, Z Liu, F He - Animal Diseases, 2024 - Springer
Nanoparticles are significant for veterinary vaccine development because they are safer and
more effective than conventional formulations. One promising area of research involves self …
more effective than conventional formulations. One promising area of research involves self …
Passive Immunity and Antibody Response Induced by Toxoplasma gondii VLP Immunization
HJ Kang, MJ Kim, KB Chu, SH Lee, EK Moon, FS Quan - Vaccines, 2021 - mdpi.com
Passive immunity can provide immediate protection against infectious pathogens. To date,
only a few studies have investigated the effect of passive immunization against Toxoplasma …
only a few studies have investigated the effect of passive immunization against Toxoplasma …
[HTML][HTML] Recent progress in vaccine development targeting pre-clinical human toxoplasmosis
KB Chu, FS Quan - Parasites, Hosts and Diseases, 2023 - ncbi.nlm.nih.gov
Toxoplasma gondii is an intracellular parasitic organism affecting all warm-blooded
vertebrates. Due to the unavailability of commercialized human T. gondii vaccine, many …
vertebrates. Due to the unavailability of commercialized human T. gondii vaccine, many …