The role of von Willebrand factor in vascular inflammation: from pathogenesis to targeted therapy
F Gragnano, S Sperlongano, E Golia… - Mediators of …, 2017 - Wiley Online Library
Beyond its role in hemostasis, von Willebrand factor (VWF) is an emerging mediator of
vascular inflammation. Recent studies highlight the involvement of VWF and its regulator …
vascular inflammation. Recent studies highlight the involvement of VWF and its regulator …
Shear stress-induced activation of von Willebrand factor and cardiovascular pathology
S Okhota, I Melnikov, Y Avtaeva, S Kozlov… - International Journal of …, 2020 - mdpi.com
The von Willebrand factor (vWF) is a plasma protein that mediates platelet adhesion and
leukocyte recruitment to vascular injury sites and carries coagulation factor VIII, a building …
leukocyte recruitment to vascular injury sites and carries coagulation factor VIII, a building …
Endothelial cell markers from clinician's perspective
J Rakocevic, D Orlic, O Mitrovic-Ajtic… - … and molecular pathology, 2017 - Elsevier
Endothelial cell markers are membrane-bound or cytoplasmic molecules expressed by
endothelial cells, which help their easier identification and discrimination from other cell …
endothelial cells, which help their easier identification and discrimination from other cell …
The role of selenium in atherosclerosis development, progression, prevention and treatment
SA Dabravolski, VN Sukhorukov, AA Melnichenko… - Biomedicines, 2023 - mdpi.com
Selenium is an essential trace element that is essential for various metabolic processes,
protection from oxidative stress and proper functioning of the cardiovascular system. Se …
protection from oxidative stress and proper functioning of the cardiovascular system. Se …
Regulation of VWF expression, and secretion in health and disease
VWF biosynthesis, maturation, and secretion is a complex process, which mandates tight
regulation. Significant progress has been made in our understandings of VWF expression …
regulation. Significant progress has been made in our understandings of VWF expression …
Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue
SF Riswari, RN Tunjungputri, V Kullaya… - PLoS …, 2019 - journals.plos.org
Thrombocytopenia and platelet dysfunction are commonly observed in patients with dengue
virus (DENV) infection and may contribute to complications such as bleeding and plasma …
virus (DENV) infection and may contribute to complications such as bleeding and plasma …
Update on ADAMTS13 and VWF in cardiovascular and hematological disorders
Endothelial cells (EC) respond to injury by releasing numerous factors, including von
Willebrand factor (VWF). High circulating levels of unusually large VWF multimers (UL …
Willebrand factor (VWF). High circulating levels of unusually large VWF multimers (UL …
Fibrinogen to HDL-Cholesterol ratio as a predictor of mortality risk in patients with acute myocardial infarction
C Jia, W Wu, H Lu, J Liu, S Chen, G Liang… - Lipids in Health and …, 2024 - Springer
Background Acute myocardial infarction (AMI) is characterized by inflammation, oxidative
stress, and atherosclerosis, contributing to increased mortality risk. High-density lipoprotein …
stress, and atherosclerosis, contributing to increased mortality risk. High-density lipoprotein …
Von Willebrand factor (vWF) in patients with heart failure with preserved ejection fraction (HFpEF): A retrospective observational study
M Abudoukelimu, B Ba, YK Guo, J Xu - Medicine, 2022 - journals.lww.com
Heart failure with preserved ejection fraction (HFpEF) is associated with endothelial damage
and inflammation. In addition, von Willebrand factor (vWF) has been discovered as a …
and inflammation. In addition, von Willebrand factor (vWF) has been discovered as a …
Von Willebrand factor and cardiovascular disease: from a biochemical marker to an attractive therapeutic target
F Gragnano, E Golia, F Natale… - Current Vascular …, 2017 - ingentaconnect.com
Background: Despite recent advances, there is still an unmet need in antithrombotic therapy.
New drugs have to overcome old targets, looking for new complementary strategies to …
New drugs have to overcome old targets, looking for new complementary strategies to …