It is important that the medical profession play a significant role in critically evaluating the
use of diagnostic procedures and therapies as they are introduced and tested in the …

Cardiovascular diseases (CVD) are the number one cause of morbidity and death
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …

The standing guideline writing committee along with the parent Task Force identified trials
and other key data through October 2011 that may impact guideline recommendations. On …

Late-breaking clinical trials presented at the 2008 and 2009 annual scientific meetings of the
ACC, AHA, and European Society of Cardiology, as well as selected other data through April …

Optimizing outcomes after percutaneous coronary intervention (PCI) requires balancing
between the risks of thrombotic and bleeding events in individual patients. 1–3 However …

Objectives: The purpose of the study was to systematically evaluate the significance of
platelet reactivity on clopidogrel treatment on adverse cardiovascular events using a …

ciation (AHA) convened a writing committee. The ACCF and AHA adhere to a rigorous policy
regarding relationships with industry and other entities (RWI) of authors and peer reviewers …

Clinical efficacy of the antiplatelet drug clopidogrel is hampered by its variable
biotransformation into the active metabolite,. The variability in the clinical response to …

Objective To evaluate the accumulated information from genetic association studies
investigating the impact of variants of the cytochrome P450 (CYP) 2C19 genotype on the …

The Society of Thoracic Surgeons (STS) Workforce on Evidence Based Surgery provides
recommendations for practicing thoracic surgeons based on available medical evidence …