MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) as new tools for cancer therapy: first steps from bench to bedside
M Ratti, A Lampis, M Ghidini, M Salati, MB Mirchev… - Targeted …, 2020 - Springer
Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …
been considered as 'junk'for a long time, non-coding RNAs are now well established as …
Competing endogenous RNA (ceRNA) cross talk and language in ceRNA regulatory networks: a new look at hallmarks of breast cancer
Breast cancer (BC) is the most frequently occurring malignancy in women worldwide.
Despite the substantial advancement in understanding the molecular mechanisms and …
Despite the substantial advancement in understanding the molecular mechanisms and …
Functions of lncRNA HOTAIR in lung cancer
G Loewen, J Jayawickramarajah, Y Zhuo… - Journal of hematology & …, 2014 - Springer
Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes.
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …
[HTML][HTML] HOTAIR: an oncogenic long non-coding RNA in different cancers
M Hajjari, A Salavaty - Cancer biology & medicine, 2015 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) refer to a group of RNAs that are usually more than 200
nucleotides and are not involved in protein generation. Instead, lncRNAs are involved in …
nucleotides and are not involved in protein generation. Instead, lncRNAs are involved in …
[HTML][HTML] Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances
R Dhanasekaran, S Bandoh, LR Roberts - F1000Research, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality and has an
increasing incidence worldwide. HCC can be induced by multiple etiologies, is influenced …
increasing incidence worldwide. HCC can be induced by multiple etiologies, is influenced …
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
WT Wang, H Ye, PP Wei, BW Han, B He… - Journal of hematology & …, 2016 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are known to play important roles in
different cell contexts, including cancers. However, little is known about lncRNAs in …
different cell contexts, including cancers. However, little is known about lncRNAs in …
A novel lncRNA uc. 134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1
W Ni, Y Zhang, Z Zhan, F Ye, Y Liang, J Huang… - Journal of hematology & …, 2017 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most common malignancies
worldwide, and tumor recurrence and metastasis are major factors that contribute to the poor …
worldwide, and tumor recurrence and metastasis are major factors that contribute to the poor …
Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity
X Chen, C Clarence Yan, C Luo, W Ji, Y Zhang… - Scientific reports, 2015 - nature.com
Increasing evidence has indicated that plenty of lncRNAs play important roles in many
critical biological processes. Developing powerful computational models to construct …
critical biological processes. Developing powerful computational models to construct …
Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA
X Chen - Scientific reports, 2015 - nature.com
Accumulating experimental studies have indicated that lncRNAs play important roles in
various critical biological process and their alterations and dysregulations have been …
various critical biological process and their alterations and dysregulations have been …
Regulatory mechanisms of long noncoding RNAs on gene expression in cancers
W Sun, Y Yang, C Xu, J Guo - Cancer genetics, 2017 - Elsevier
Highlights•Long non-coding RNAs (lncRNAs) are a heterogeneous class of RNAs.•By acting
as signal, guide, decoy or scaffold, lncRNAs are involved in several types of diseases …
as signal, guide, decoy or scaffold, lncRNAs are involved in several types of diseases …