Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

Generating force and movement is essential for the functions of cells and organisms. A
variety of molecular motors that can move on tracks within cells have evolved to serve this …

Slender bundled actin containing plasma membrane protrusions, called filopodia, are
important for many essential cellular processes like cell adhesion, migration, angiogenesis …

Integrin-dependent cell adhesions come in different shapes and serve in different cell types
for tasks ranging from cell-adhesion, migration, and the remodeling of the extracellular …

The kinesin-3 family is one of the largest among the kinesin superfamily and its members
play important roles in a wide range of cellular transport activities, yet the molecular …

As the prototype of unconventional myosin motor family, myosin Va (MyoVa) transport
cellular cargos along actin filaments in diverse cellular processes. The off-duty MyoVa …

Mutations of the tumor suppressor TP53 are present in many forms of human cancer and are
associated with increased tumor cell invasion and metastasis. Several mechanisms have …

Members of the myosin superfamily are actin-based molecular motors that are
indispensable for cellular homeostasis. The vast functional and structural diversity of …

Cell-to-cell communication is essential in multicellular organisms. Tunneling nanotubes
(TNTs) have emerged as a new type of intercellular spreading mechanism allowing the …

The delivery of intracellular material within cells is crucial for maintaining normal function.
Myosins transport a wide variety of cargo, ranging from vesicles to ribonuclear protein …