Stress and cancer: mechanisms, significance and future directions
A Eckerling, I Ricon-Becker, L Sorski… - Nature Reviews …, 2021 - nature.com
The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …
More recent animal studies indicate that stress can substantially facilitate cancer …
Antidepressants for the treatment of depression in people with cancer
Background Major depression and other depressive conditions are common in people with
cancer. These conditions are not easily detectable in clinical practice, due to the overlap …
cancer. These conditions are not easily detectable in clinical practice, due to the overlap …
Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils
M Perego, VA Tyurin, YY Tyurina, J Yellets… - Science translational …, 2020 - science.org
Tumor recurrence years after seemingly successful treatment of primary tumors is one of the
major causes of mortality in patients with cancer. Reactivation of dormant tumor cells is …
major causes of mortality in patients with cancer. Reactivation of dormant tumor cells is …
Understanding the role of dopamine in cancer: past, present and future
Abstract Dopamine (DA, 3-hydroxytyramine) is a member of the catecholamine family and is
classically characterized according to its role in the central nervous system as a …
classically characterized according to its role in the central nervous system as a …
Suppression of EGFR/PKC-δ/NF-κB signaling associated with imipramine-inhibited progression of non-small cell lung cancer
PF Yueh, YH Lee, IT Chiang, WT Chen, KL Lan… - Frontiers in …, 2021 - frontiersin.org
Background Anti-depressants have been reported to own anti-tumor potential types of
cancers; however, the role of imipramine in non-small cell lung cancer (NSCLC) has not …
cancers; however, the role of imipramine in non-small cell lung cancer (NSCLC) has not …
Understanding and modeling nerve–cancer interactions
The peripheral nervous system plays an important role in cancer progression. Studies in
multiple cancer types have shown that higher intratumoral nerve density is associated with …
multiple cancer types have shown that higher intratumoral nerve density is associated with …
Antidepressant use and mortality among patients with hepatocellular carcinoma
Importance Liver cancer, primarily hepatocellular carcinoma (HCC), is the third leading
cause of cancer deaths worldwide. Although some studies have proposed that …
cause of cancer deaths worldwide. Although some studies have proposed that …
Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy
PED Chung, DMA Gendoo… - Nature …, 2020 - nature.com
Pineoblastoma is a rare pediatric cancer induced by germline mutations in the tumor
suppressors RB1 or DICER1. Presence of leptomeningeal metastases is indicative of poor …
suppressors RB1 or DICER1. Presence of leptomeningeal metastases is indicative of poor …
Monotherapy efficacy of blood–brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma
J Merisaari, OV Denisova, M Doroszko… - Brain …, 2020 - academic.oup.com
Glioblastoma is a fatal disease in which most targeted therapies have clinically failed.
However, pharmacological reactivation of tumour suppressors has not been thoroughly …
However, pharmacological reactivation of tumour suppressors has not been thoroughly …
HTR1A Inhibits the Progression of Triple‐Negative Breast Cancer via TGF‐β Canonical and Noncanonical Pathways
Q Liu, H Sun, Y Liu, X Li, B Xu, L Li, W Jin - Advanced Science, 2022 - Wiley Online Library
Triple‐negative breast cancer is the most aggressive subtype of breast cancer and the
incidence of depression in breast cancer patients is high, which leading to worse survival …
incidence of depression in breast cancer patients is high, which leading to worse survival …