Machine learning-enabled retrobiosynthesis of molecules

T Yu, AG Boob, MJ Volk, X Liu, H Cui, H Zhao - Nature Catalysis, 2023 - nature.com
Retrobiosynthesis provides an effective and sustainable approach to producing functional
molecules. The past few decades have witnessed a rapid expansion of biosynthetic …

Into the unknown: how computation can help explore uncharted material space

AM Mroz, V Posligua, A Tarzia… - Journal of the …, 2022 - ACS Publications
Novel functional materials are urgently needed to help combat the major global challenges
facing humanity, such as climate change and resource scarcity. Yet, the traditional …

Genetic algorithms for the discovery of homogeneous catalysts

S Gallarati, P Van Gerwen, AA Schoepfer, R Laplaza… - Chimia, 2023 - chimia.ch
In this account, we discuss the use of genetic algorithms in the inverse design process of
homogeneous catalysts for chemical transformations. We describe the main components of …

Reaction mechanism–explored with the unified reaction valley approach

E Kraka, JJ Antonio, M Freindorf - Chemical Communications, 2023 - pubs.rsc.org
One of the ultimate goals of chemistry is to understand and manipulate chemical reactions,
which implies the ability to monitor the reaction and its underlying mechanism at an atomic …

Tensorizing flows: a tool for variational inference

Y Khoo, M Lindsey, H Zhao - arXiv preprint arXiv:2305.02460, 2023 - arxiv.org
Fueled by the expressive power of deep neural networks, normalizing flows have achieved
spectacular success in generative modeling, or learning to draw new samples from a …

Data-driven plasma modelling: surrogate collisional radiative models of fluorocarbon plasmas from deep generative autoencoders

GA Daly, JE Fieldsend, G Hassall… - … Learning: Science and …, 2023 - iopscience.iop.org
We have developed a deep generative model that can produce accurate optical emission
spectra and colour images of an ICP plasma using only the applied coil power, electrode …

[HTML][HTML] Toward implementing autonomous adaptive data acquisition for scanning hyperspectral imaging of biological systems

EA Holman, H Krishnan, DR Holman… - Applied Physics …, 2023 - pubs.aip.org
Autonomous experimentation is an emerging area of research, primarily related to
autonomous vehicles, scientific combinatorial discovery approaches in materials science …

Coupling chemistry and biology for the synthesis of advanced bioproducts

Y Chainani, G Bonnanzio, KEJ Tyo… - Current Opinion in …, 2023 - Elsevier
Highlights•Biology can expand the scope of chemical manufacturing, but limitations
persist.•Green chemistry offers a sustainable alternative to petrochemical …

Fault self-healing: A biological immune heuristic reinforcement learning method with root cause reasoning in industrial manufacturing process

JY Tian, M Yin, J Jiang - Engineering Applications of Artificial Intelligence, 2024 - Elsevier
Stable fault self-healing ensures the smooth operation of intelligent industrial manufacturing
processes. However, current research, while capable of inferring fault propagation paths or …

Leveraging attention-enhanced variational autoencoders: Novel approach for investigating latent space of aptamer sequences

A Salimi, JH Jang, JY Lee - International Journal of Biological …, 2024 - Elsevier
Aptamers are increasingly recognized as potent alternatives to antibodies for diagnostic and
therapeutic applications. The application of deep learning, particularly attention-based …